Clinical Pharmacist Anticoagulant Stewardship

NCT ID: NCT03527615

Last Updated: 2018-05-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

4000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2020-01-01

Brief Summary

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Initiative to improve direct anticoagulant utilization involving programmatic review by clinical pharmacists in collaboration with multidisciplinary team.

Detailed Description

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The Hadassah Hebrew University Medical Centers' Clinical Pharmacy team initiated a hospital-wide program, in collaboration with the institutions' coagulation specialists, including two hematologists and a clinical pharmacologist, for monitoring and promoting safe and effective prescription of direct oral anticoagulants (DOAC) during hospitalization. Electronic medical records throughout the hospital are screened for DOAC orders. All DOAC orders are assessed by a clinical pharmacist for potentially-inappropriate prescribing. When potentially-inappropriate prescribing or a drug-related problem is identified, the clinical pharmacist provided consultation on management options. In specific cases, additional guidance is provided by coagulation specialists. Consultations are recorded in the electronic medical record. Performance measures are collected and summarized.

Conditions

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Safety Issues Anticoagulant Toxicity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Clinical Pharmacist Medication Review

Programmatic review of physician orders for direct anticoagulants by clinical pharmacists.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Patients hospitalized in Hadassah Medical Center with a physician's order for direct oral anticoagulants (apixaban, rivaroxaban, or dabigatran).

Exclusion Criteria

Patients hospitalized in departments without computerized physician order entry.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hadassah Medical Organization

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mordechai Muszkat, MD

Role: PRINCIPAL_INVESTIGATOR

Hadassah University Medical Center

Locations

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Hadassah Medical Organization, Jerusalem, Israel

Jerusalem, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Amichai Perlman, Pharmd

Role: CONTACT

972505172768

Facility Contacts

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Hadas Lemberg, PhD

Role: primary

00 972 2 6777572

References

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Perlman A, Horwitz E, Hirsh-Raccah B, Aldouby-Bier G, Fisher Negev T, Hochberg-Klein S, Kalish Y, Muszkat M. Clinical pharmacist led hospital-wide direct oral anticoagulant stewardship program. Isr J Health Policy Res. 2019 Feb 1;8(1):19. doi: 10.1186/s13584-019-0285-9.

Reference Type DERIVED
PMID: 30709417 (View on PubMed)

Other Identifiers

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DOACPHARM-HMO-CTIL

Identifier Type: -

Identifier Source: org_study_id

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