Trial Outcomes & Findings for A Prospective Study to Evaluate Robot Assisted Total Knee Replacement Outcomes (NCT NCT03523897)

NCT ID: NCT03523897

Last Updated: 2025-06-06

Results Overview

The FJS is a self-completed 12-item questionnaire used to assess patients' awareness of their artificial joint during activities of daily living on an awareness scale of 0 (never) to 4 (mostly)

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

92 participants

Primary outcome timeframe

1 year

Results posted on

2025-06-06

Participant Flow

Participant milestones

Participant milestones
Measure
Robot Assisted Total Knee Replacement
In addition to expert judgment and hand-eye coordination, the surgeon also relies on a robot in making cuts within the pre-determined diseased areas of the joints and placing the implants. This is made possible by uploading 3-dimensional (3D) images of the knee joints into the robot prior to surgery. The robot uses these 3D images to guide the surgeon during the procedure. The 3D images are obtained from a computerized tomography (CT) scan that combines a series of X-ray images taken from different angles to create cross-sectional images of the bones. Robot Assisted Total Knee Replacement: A robotic-assisted surgical procedure to treat a condition in which the patient's knee joints become diseased or injured due to a loss of cartilage that acts as a protective cushion between the knee joints
Traditional Total Knee Replacement
The traditional method where the surgeon employs mechanical guides, expert judgment, and natural hand-eye coordination in making the necessary cuts to prepare the bone for the implant as well as in placing the implant. Traditional Total Knee Replacement: A surgical procedure using mechanical guides to treat a condition in which the patient's knee joints become diseased or injured due to a loss of cartilage that acts as a protective cushion between the knee joints
Overall Study
STARTED
39
53
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
39
53

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

A Prospective Study to Evaluate Robot Assisted Total Knee Replacement Outcomes

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Robot Assisted Total Knee Replacement
n=39 Participants
In addition to expert judgment and hand-eye coordination, the surgeon also relies on a robot in making cuts within the pre-determined diseased areas of the joints and placing the implants. This is made possible by uploading 3-dimensional (3D) images of the knee joints into the robot prior to surgery. The robot uses these 3D images to guide the surgeon during the procedure. The 3D images are obtained from a computerized tomography (CT) scan that combines a series of X-ray images taken from different angles to create cross-sectional images of the bones. Robot Assisted Total Knee Replacement: A robotic-assisted surgical procedure to treat a condition in which the patient's knee joints become diseased or injured due to a loss of cartilage that acts as a protective cushion between the knee joints
Traditional Total Knee Replacement
n=53 Participants
The traditional method where the surgeon employs mechanical guides, expert judgment, and natural hand-eye coordination in making the necessary cuts to prepare the bone for the implant as well as in placing the implant. Traditional Total Knee Replacement: A surgical procedure using mechanical guides to treat a condition in which the patient's knee joints become diseased or injured due to a loss of cartilage that acts as a protective cushion between the knee joints
Total
n=92 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
1 Participants
n=5 Participants
0 Participants
n=7 Participants
1 Participants
n=5 Participants
Age, Categorical
>=65 years
38 Participants
n=5 Participants
53 Participants
n=7 Participants
91 Participants
n=5 Participants
Sex: Female, Male
Female
26 Participants
n=5 Participants
33 Participants
n=7 Participants
59 Participants
n=5 Participants
Sex: Female, Male
Male
13 Participants
n=5 Participants
20 Participants
n=7 Participants
33 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=5 Participants
1 Participants
n=7 Participants
1 Participants
n=5 Participants
Race (NIH/OMB)
White
38 Participants
n=5 Participants
51 Participants
n=7 Participants
89 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
1 Participants
n=5 Participants
1 Participants
n=7 Participants
2 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Region of Enrollment
United States
39 participants
n=5 Participants
53 participants
n=7 Participants
92 participants
n=5 Participants

PRIMARY outcome

Timeframe: 1 year

Population: Study canceled due to lack of resources. The personnel responsible for collecting data left the hospital system before any data was collected and the investigators involved did not have the time necessary to collect and organize data. Therefore, no data was collected at the 1-year timeframe, leading to no data available for analysis.

The FJS is a self-completed 12-item questionnaire used to assess patients' awareness of their artificial joint during activities of daily living on an awareness scale of 0 (never) to 4 (mostly)

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 1 year

Population: Study canceled due to lack of resources. The personnel responsible for collecting data left the hospital system before any data was collected and the investigators involved did not have the time necessary to collect and organize data. Therefore, no data was collected at the 1-year timeframe, leading to no data available for analysis.

The KOOS is a knee-specific instrument used to evaluate short-term and long-term symptoms and function in subjects with knee injury and osteoarthritis. It consists of 42 questions in 5 subscales; Pain, other Symptoms, Function in daily living (ADL), Function in Sport and Recreation (Sport/Rec), and knee-related Quality of Life (QOL).

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 1 year

The VR-12 is a 12-item questionnaire corresponding to eight principal physical and mental health domains including general health perceptions, physical functioning, role limitations due to physical and emotional problems, bodily pain, energy-fatigue, social functioning and mental health.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 weeks postoperatively

The mechanical alignment of the entire post-operative limb will be measured at 6 weeks by long-limb radiograph cassettes and compared to the pre-operative plan for accuracy and deviation less than or greater than 3 degrees from the intended target. From each treatment group, the percentage of patients with radiographic outliers (deviation greater that 3 degrees from the expected implant placement) will be compared.

Outcome measures

Outcome data not reported

Adverse Events

Robot Assisted Total Knee Replacement

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Traditional Total Knee Replacement

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Jeremy Reid

Virtua Health

Phone: 8008967326

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place