Trial Outcomes & Findings for Testing an Implementation Science Tool to Increase Cervical Cancer Screening in Mombasa, Kenya (NCT NCT03514459)

NCT ID: NCT03514459

Last Updated: 2024-05-22

Results Overview

Proportion of all FP clients aged 21-65 years who were screened for cervical cancer over the total number of eligible clients

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

20 participants

Primary outcome timeframe

Aggregated data across 18 months, individual participants were not followed over time.

Results posted on

2024-05-22

Participant Flow

Family planning clinics were the unit of randomization and whole clinics were randomized to intervention arm or control arm. Individual participants were not enrolled. Outcomes about women were aggregated across each clinic and not all individual level data including age were collected as we were using paper registry records with identifiable information redacted.

Unit of analysis: Family planning clinics

Participant milestones

Participant milestones
Measure
Intervention With SAIA
Systems Analysis and Improvement Approach: SAIA has five steps. The first step uses an Excel-based tool to quantify drop- offs, or people who did not progress, in each step of a process (Figure 1). This tool also allows the user to see the downstream effect when improving one step in the cascade, and holding the other steps constant. Step 2 involves process flow mapping with clinic staff to identify modifiable bottlenecks in the process. Step 3 develops and implements a workflow modification to address a bottleneck identified in step 2 (continuous quality improvement \[CQI\] step). Step 4 assesses impact of the modification and recalculates the cascade analysis in step 1 (CQI step). Step 5 repeats the cycle for CQI. SAIA draws from systems engineering in the Toyota Production Systems and from research in LMICs. Studies in quality improvement in LMICs highlight that CQI processes led to more sustainable, effective, and appropriate interventions (42-44).
Control Arm
Following usual procedures
Overall Study
STARTED
0 10
0 10
Overall Study
COMPLETED
0 10
0 10
Overall Study
NOT COMPLETED
0 0
0 0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Testing an Implementation Science Tool to Increase Cervical Cancer Screening in Mombasa, Kenya

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: Aggregated data across 18 months, individual participants were not followed over time.

Population: These are aggregated participants in intervention and control clinics. Individual participants were not enrolled in the trial as this was a cluster randomized trial. Results are aggregated across all clinics and presented here but these are not RCT participants as they were not enrolled.

Proportion of all FP clients aged 21-65 years who were screened for cervical cancer over the total number of eligible clients

Outcome measures

Outcome measures
Measure
Control
n=10 Family planning clinics
Control clinics: Clinics randomized to the control arm will continue usual procedures. Periodic evaluation of cervical cancer screening rates will be examined every 3 months using FP register data.
Intervention With SAIA
n=10 Family planning clinics
Systems Analysis and Improvement Approach: SAIA has five steps. The first step uses an Excel-based tool to quantify drop- offs, or people who did not progress, in each step of a process (Figure 1). This tool also allows the user to see the downstream effect when improving one step in the cascade, and holding the other steps constant. Step 2 involves process flow mapping with clinic staff to identify modifiable bottlenecks in the process. Step 3 develops and implements a workflow modification to address a bottleneck identified in step 2 (continuous quality improvement \[CQI\] step). Step 4 assesses impact of the modification and recalculates the cascade analysis in step 1 (CQI step). Step 5 repeats the cycle for CQI. SAIA draws from systems engineering in the Toyota Production Systems and from research in LMICs. Studies in quality improvement in LMICs highlight that CQI processes led to more sustainable, effective, and appropriate interventions (42-44).
Cervical Cancer Screening
198 individuals screened
289 individuals screened

Adverse Events

Control--no Individual Participants Enrolled

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Intervention With SAIA--no Individual Participants Enrolled

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. McKenna Eastment

University of Washington

Phone: 5742101120

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place