Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
58 participants
INTERVENTIONAL
2017-04-05
2019-05-21
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Salbutamol loading dose
Salbutamol loading dose of 15 mcg/kg in 10 minutes, with a maximum of 750 mcg.
Salbutamol
Intravenous Salbutamol loading dose
Sodium Chloride 0.9%
10 ml of Sodium Chloride 0.9% in 10 minutes.
Sodium Chloride 0.9%
10 ml of Sodium Chloride 0.9% in 10 minutes intravenous
Interventions
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Salbutamol
Intravenous Salbutamol loading dose
Sodium Chloride 0.9%
10 ml of Sodium Chloride 0.9% in 10 minutes intravenous
Eligibility Criteria
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Inclusion Criteria
* Admitted to PICU for Severe Acute Asthma or Severe acute (viral) wheeze
* Requiring administration of IV salbutamol
Exclusion Criteria
* Patient has already received a -loading dose- of IV salbutamol in the general hospital
* Lower airway infection with consolidation on a chest X ray -Patient has Down's Syndrome
* Patient has a congenital/acquired heart defect that interferes with normal asthma treatment
* Patient has a primary/secondary immunodeficiency
* Patient has a pre-existing chronic pulmonary condition, known to mimic asthma: Cystic fibrosis, Bronchopulmonary dysplasia, Bronchiolitis obliterans
2 Years
18 Years
ALL
No
Sponsors
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Erasmus Medical Center
OTHER
Responsible Party
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Matthijs de Hoog
Principal Investigator
Locations
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Erasmus MC
Rotterdam, South Holland, Netherlands
Countries
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Other Identifiers
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NL55029.078.16
Identifier Type: -
Identifier Source: org_study_id
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