Ovarian Reserve in Patients With Psoriasis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

72 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-10-25

Study Completion Date

2018-07-03

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Psoriasis is a common autoimmune disease. It affects women of all ages including reproductive years. Autoimmune diseases including psoriasis are linked to premature ovarian reserve. This study aims to measure serum hormones including FSH,LH,E2,PRL and AMH (indicators of ovarian reserve) in women with and without psoriasis.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Ovarian Reserve and Matrix Metalloproteinases

NCT05443282

Oxidative Stress Ovarian Insufficiency, Primary Ovarian Failure, Premature

COMPLETED

Ovarian Reserve in Diabetes Mellitus

NCT03859856

Type1 Diabetes Mellitus

COMPLETED

Serum Anti-Mullerian Hormone (AMH) Levels in Overweight and Obese Adolescent Girls With Polycystic Ovaries

NCT01856894

Polycystic Ovary Syndrome

COMPLETED

The Role of Autoimmunity and Obesity in Polycystic Ovary Syndrome

NCT05929950

Polycystic Ovary Syndrome

UNKNOWN

Oxidative Stress in Polycystic Ovary Syndrome With Periodontal Disease and Dental Caries Lesions

NCT03594968

Polycystic Ovary Syndrome Dental Caries

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Psoriasis is a common autoimmune disease. It affects women of all ages including reproductive years. Almost 75% of patients are diagnosed before the age of 40. There is also increased evidence on autoimmune disease and their link to premature ovarian failure.Ovarian reserve is important for the reproductive period. The measurements of serum hormones including follicle stimulating hormone (FSH),luteinizing hormone (LH),prolactin (PRL), estradiol (E2) and anti-mullerian hormone (AMH) will give us an idea about the ovarian reserve. The investigators aim is to measure ovarian reserve parameters in patients newly diagnosed with psoriasis and to compare them to healthy controls. Serum FSH,LH,E2,PRL and AMH will be measured on the 3rd day of the cycle.The serum hormone levels will be compared between women with psoriasis and women without psoriasis

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Psoriasis Anti Mullerian Hormone Ovarian Reserve

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Women with Psoriasis

Reproductive age women newly diagnosed with psoriasis

Hormone panel

Intervention Type OTHER

Blood sampling on the 3rd day of menstrual cycle for the measurement of serum FSH,LH,PRL,E2 and AMH hormone levels.

Women without Psoriasis

Reproductive age women without psoriasis to serve as control

Hormone panel

Intervention Type OTHER

Blood sampling on the 3rd day of menstrual cycle for the measurement of serum FSH,LH,PRL,E2 and AMH hormone levels.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Hormone panel

Blood sampling on the 3rd day of menstrual cycle for the measurement of serum FSH,LH,PRL,E2 and AMH hormone levels.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Reproductive age group women: 18-40 years
* Women diagnosed with psoriasis (case group)
* Women without psoriasis (control group)

Exclusion Criteria

* Women with PCOS (polycystic ovary syndrome)
* history of ovarian surgery
* Body mass index (BMI) over 30
* Women with other autoimmune diseases including Hashitomo thyroiditis
* Women with family history of premature ovarian insufficiency (POI)
* Women with infertility
* Psoriasis using systemic drugs including steroids and immunosuppressive therapy.

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes