Role of Antibiotics Post Tonsillectomy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

PHASE1/PHASE2

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-05-15

Study Completion Date

2020-03-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

morbidity after tonsillictomy remains asignificant problem therefore they recommend prophylactic antibiotics to reduce it.in the other hand, the overuse of antimicrobial agents can lead to antimicrobial resistance ,adverse drug events,and unnecessary cost.so,the effectiveness and necessity of antibiotic following tonsillictomy needs to be studied .

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of Duration of Antibiotic Therapy on Recovery Following Tonsillectomy

NCT00662987

Tonsillectomy

COMPLETED NA

Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use

NCT01561703

Snoring Strep Throat

COMPLETED NA

Outpatient Management of Tonsillectomy in Adults

NCT05915559

Tonsillectomy Pain Ambulatory

ACTIVE_NOT_RECRUITING NA

Tonsillectomy in Recurrent Tonsillitis

NCT00136877

Tonsillitis

UNKNOWN NA

Recurrent Throat Infections and Tonsillectomy

NCT00547391

Tonsillitis Pharyngitis

COMPLETED PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Tonsillectomy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

tonsillictomy with antibiotics

Group Type ACTIVE_COMPARATOR

Amoxicillin/clavulanate

Intervention Type DRUG

after tonsillectomy half of our patients will receive Amoxicillin /clavulanate for one week and the other half will not receive it.

tonsillictomy Without Antibiotics

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Amoxicillin/clavulanate

after tonsillectomy half of our patients will receive Amoxicillin /clavulanate for one week and the other half will not receive it.

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

200 patients who are scheduled for tonsillectomy with or without adenoidectomy, and their age are less than 18 years old of either gender will be included in our study

Exclusion Criteria

* 1-Patients age ≥ 18 years.

2-Trials in which antibiotics was administrated locally or used in the immediate preoperative period (within seven days before surgery).

3\. Medical comorbidity requiring treatment with antibiotics e.g. Rheumatic heart disease

4-Patients undergoing the following procedures:
1. Unilateral tonsillectomy or biopsy.
2. Tonsillectomy for known carcinoma.
3. Tonsillectomy in conjunction with palatal surgery.
4. Hot tonsillectomy for tonsillar abscess

Minimum Eligible Age

1 Year

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No