Microwave Ablation in Ground Glass Nodules

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-05-01

Study Completion Date

2025-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

GGO was commonly observed recently.Radiofrequency ablation has been widely applied in the treatment of patients with GGO. No study had explored the microwave ablation in the treatment of GGO.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Transbronchial Ablation for Peripheral Lung Tumor

NCT02972177

Lung Cancer

UNKNOWN NA

Radiofrequency Ablation Combined With Chemotherapy for Pulmonary Tumors

NCT01105182

NSCLC Pulmonary Metastases

UNKNOWN

Transbronchial MWA for Pulmonary Tumors

NCT06969014

Lung Cancer

RECRUITING NA

Radiofrequency Ablation of Pulmonary Tumors Response Evaluation

NCT00690703

Non Small Cell Lung Cancer Pulmonary Metastases

COMPLETED PHASE2

Preoperative Percutaneous Radiofrequency Ablation of Primary and Secondary Lung Tumors

NCT00610844

Lung Cancer Lung Metastasis

COMPLETED PHASE2

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

GGO was common with the development of image. Treatments of GGO include radical surgery and irradiation. For patients who were poor candidate of surgery, image guided thermal ablation could be an alternative.Radiofrequency ablation has been widely applied in the treatment of eary-stage non small cell lung cancer and those patients with GGO. However, up to date, no study had explored the microwave ablation in the treatment of GGO.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Microwave Ablation Lung Cancer

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

All patient with GGO were treated with microwave ablation

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

All patient with GGO were treated with microwave ablation

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Microwave ablation in the GGO

Patients with GGO were treated with microwave ablation.

Group Type EXPERIMENTAL

Microwave ablaton

Intervention Type OTHER

Patients with pathology verified GGO were treated with MWA.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Microwave ablaton

Patients with pathology verified GGO were treated with MWA.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Patient has a histologically verified AIS or MIA.
2. The tumors small enough to treat (usually ≤3 cm), and without chest pleura invasion.
3. Solid cements in the GGO less than 50%.
4. No other sites of disease observed.
5. Patient is not a candidate for surgical removal of the cancer, or refused surgery.
6. Patient is not a candidate for radiation therapy, or refused radiation therapy.
7. Patient has \> 6 month life expectancy.
8. Eastern Cooperative Oncology Group performance status of 0 to 2.
9. No prior anticancer treatments including surgery, radiation,chemotherapy or local treatments.
10. Sufficient organ functions.
11. Written informed consent.

Exclusion Criteria

1. Active bacterial or fungous infection.
2. Simultaneous or metachronous (within the past 5 years) double cancers.
3. Women during pregnancy or breast-feeding.
4. Interstitial pneumonitis, pulmonary fibrosis, or severe pulmonary emphysema.
5. Uncontrollable diabetes mellitus. History of severe heart disease, heart failure, myocardial infarction within the past 6 months or attack of angina pectoris within the past 6 months.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No