Essential Tremor in Children and Adolescent

NCT ID: NCT03487705

Last Updated: 2021-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

18 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-01

Study Completion Date

2021-07-02

Brief Summary

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Essential tremor (TE) is the most common abnormal movement of the adult. His diagnosis is based on a bundle of clinical arguments (Movement Disorders Society, 1998). Well characterized in the adult, little data is available concerning child. The objective of this work is (1) to define the demographic and clinical characteristics of the TE of children and adolescents, (2) to determine the electrophysiological characteristics in the child, (3) evaluate the functional impact of TE, and assess the functional impact of TE, and assess the current management modalities of TE in children and adolescent.

Detailed Description

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A multicenter, descriptive cross-sectional study will include children and adolescents whose diagnosis of TE has been retained by an abnormal movement specialist before the age of 18 years.

Each child will benefit from an examination and a neurological and general clinical examination, a functional questionnaire, an electromyogram with accelerometer.

Will be determined: demographic characteristics (age, sex and ethnicity), family history of essential tremor, age of onset of tremor, tremor characteristics (location, occurrence conditions, aggravating or precipitating factors, scalability); additional examinations carried out and the treatments proposed or taken by the child as well as the functional repercussions of TE in the child.

Patients with tremor who meet the inclusion and exclusion criteria will be selected retrospectively or prospectively from the active queue of patients at each center.

Conditions

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Essential Tremor

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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child essential tremor

electromyogram with accelerometer

Group Type OTHER

electromyographic essential tremor

Intervention Type OTHER

* Making a recording electromyographic recording of the essential tremors in each child included at prospective.
* Collect an electromyographic recording of essential tremors already made in each child included at retrospective.

Interventions

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electromyographic essential tremor

* Making a recording electromyographic recording of the essential tremors in each child included at prospective.
* Collect an electromyographic recording of essential tremors already made in each child included at retrospective.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subject whose age is between 3 and 18 years
* Subject affiliated to a social security scheme
* Parents or subjects who have been informed of the course and consequences of the study by an investigator and who have signed the informed consent form for prospective inclusion or who have given their non-opposition for retrospective inclusion.
* Diagnosis of essential tremor established according to the diagnostic criteria of the Movement Disorders Society (1998), by a neuropediatrician or a neurologist, specialist in abnormal movements. The diagnosis is based on the presence of the following criteria: bilateral action tremor of the hands and forearms, absence of other neurological signs.
* Availability of an electromyogram for retrospective inclusions.

Exclusion Criteria

* Abnormal neurological examination outside tremor
* Family history or personal dysthyroidism
* Existence of a global psychomotor or motor developmental delay
* Taking medication that may induce tremor
* known poisoning by heavy metals, bismuth, mercury, methyl bromide
* Severe appearance of the tremor
* Tremor suggestive of a psychogenic origin
* Abnormal or non-existent brain MRI if family case
Minimum Eligible Age

3 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Montpellier

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Agathe ROUBERTIE, Pr

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Montpellier

Locations

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CHU Gui de Chauliac

Montpellier, , France

Site Status

Countries

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France

Other Identifiers

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UF9770

Identifier Type: -

Identifier Source: org_study_id