Characterization of White Blood Cells Sub-populations From Multiple Sclerosis Patients.

NCT ID: NCT03486665

Last Updated: 2018-07-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-04-24

Study Completion Date

2020-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Multiple sclerosis (MS) is a chronic progressive neurological autoimmune disease, that gradually affects patient's quality of life. There are about 2.5 millions patients world wide, with an increasing cost Burdon. Up to date, it remains unclear who are the exact cells to initiate the disease. During the disease, the repertoire of cells expands and undergoes changes. The purpose of this study is to characterize those changes.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Multiple Sclerosis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Diagnosed with Multiple Sclerosis

Patients previously diagnosed with Multiple Sclerosis

Blood Sampling

Intervention Type OTHER

Blood samples will be taken from all patients and healthy volunteers.

Newly Diagnosed with Multiple Sclerosis

Patients diagnosed for the first time with Multiple Sclerosis and hospitalized

Blood Sampling

Intervention Type OTHER

Blood samples will be taken from all patients and healthy volunteers.

CSF Sampling

Intervention Type OTHER

CSF sample will be taken from hospitalized newly diagnosed patients only.

Healthy Volunteers

Health volunteers who do not have an autoimmune diseases, including Multiple Sclerosis

Blood Sampling

Intervention Type OTHER

Blood samples will be taken from all patients and healthy volunteers.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Blood Sampling

Blood samples will be taken from all patients and healthy volunteers.

Intervention Type OTHER

CSF Sampling

CSF sample will be taken from hospitalized newly diagnosed patients only.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients with diagnosis of MS according to the revised criteria of McDonald or healthy volunteers
* Ability to provide written informed consent.

Exclusion Criteria

\- Active malignant disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Bioimmunate

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hadassah Medical Center

Jerusalem, , Israel

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Israel

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Sigalit Carmel, MD, MSc

Role: CONTACT

+97225649302

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Ariel Ginzberg, PHD

Role: primary

+972 2 6776939

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

BIT-001

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Immunodeficiency in MS
NCT04447937 UNKNOWN