Hyperspectral Imaging for Neoplasm Early Stage Detection
NCT ID: NCT03483974
Last Updated: 2018-03-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2017-08-01
2018-09-30
Brief Summary
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Material and Methods This research intended to enroll one hundred patients into the study. This includes patients with positive stool or urine analysis admitted for workup of colorectal cancer. We will scan the stool and urine with hyperspectral imaging sensoroptical spectrometer, which utilize multichannel charge-coupled device and InGaAs array to analyze the full spectrum of light patterns. The image pattern will be stored and used to linked final diagnosis. Absorption, scattering, and reflection spectra are expected for analysis. Follow up analysis after cancer staging will be used for lowering background noise in all spectra.
Expected Results We expect that there will be specific spectral pattern in stool of colorectal cancer patients, which may be related with cancer staging and different from those in patients without malignancy. Difference in spectra will lead to discovery of new biomarker for colorectal cancer and related diseases. The optic spectra pattern of stool and urine may assist early diagnosis and staging of different malignancies
Detailed Description
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Material and Methods This research intended to enroll one hundred patients into the study. This includes patients with positive stool or urine analysis admitted for workup of colorectal cancer. We will scan the stool and urine with hyperspectral imaging sensoroptical spectrometer, which utilize multichannel charge-coupled device and InGaAs array to analyze the full spectrum of light patterns. The image pattern will be stored and used to linked final diagnosis. Absorption, scattering, and reflection spectra are expected for analysis. Follow up analysis after cancer staging will be used for lowering background noise in all spectra.
Expected Results We expect that there will be specific spectral pattern in stool of colorectal cancer patients, which may be related with cancer staging and different from those in patients without malignancy. Difference in spectra will lead to discovery of new biomarker for colorectal cancer and related diseases. The optic spectra pattern of stool and urine may assist early diagnosis and staging of different malignancies
Conditions
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Keywords
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Study Design
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ECOLOGIC_OR_COMMUNITY
PROSPECTIVE
Study Groups
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neoplasm
neoplasm found in follow up
hyperspectral imaging
using hyperspectral detector for evaluation excreta pattern
non-neoplasm
non-neoplasm patients in follow up
hyperspectral imaging
using hyperspectral detector for evaluation excreta pattern
Interventions
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hyperspectral imaging
using hyperspectral detector for evaluation excreta pattern
Eligibility Criteria
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Inclusion Criteria
* above 20 year-old
* previous stool or urine analysis negative 8 weeks ago
Exclusion Criteria
* active gastrointestinal disease one year ago
* active infection
* having surgery within a year
* underlying active gastrointestinal, urinary tract, and coagulation disease
20 Years
ALL
No
Sponsors
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Chang Gung Memorial Hospital
OTHER
Responsible Party
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Dong-Ru Ho
Assistant Professor
Locations
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Dong-Ru Ho
Chiayi City, , Taiwan
Countries
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Central Contacts
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Facility Contacts
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DONG-RU HO
Role: primary
Other Identifiers
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201701068B0
Identifier Type: -
Identifier Source: org_study_id