Interstitial Brachytherapy Boost for Treatment of Anal Canal Cancers, Comparison of Two Dose Rates

NCT ID: NCT03465501

Last Updated: 2018-03-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

89 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-08-17

Study Completion Date

2016-07-28

Brief Summary

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Comparative retrospective study of two anal canal brachytherapy techniques aimed at boosting \[low dose rate (LDR) and high dose rate (HDR)\]

Detailed Description

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Efficacy of anal canal interstitial brachytherapy evaluated by local relapse rate, Tolerance of interstitial brachytherapy of the anal canal evaluated by the rate of chronic toxicities.

Conditions

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Anal Canal Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Low Dose Rate

Patients treated with brachytherapy at low dose rate of the anal canal with aim of boost

Brachytherapy

Intervention Type RADIATION

Brachytherapy

High Dose Rate

Patients treated by brachytherapy with a high dose rate of the anal canal aiming for boost

Brachytherapy

Intervention Type RADIATION

Brachytherapy

Interventions

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Brachytherapy

Brachytherapy

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Patients treated by brachytherapy anal canal to boost.

Exclusion Criteria

* Patients below age of 18 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Institut Paoli-Calmettes

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Leonel VARELA GAGETTI

Role: PRINCIPAL_INVESTIGATOR

Institut Paoli-Calmettes

Locations

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Institut Paoli Calmettes

Marseille, Bouches Du Rhone, France

Site Status

Countries

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France

References

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Cordoba A, Escande A, Leroy T, Mirabel X, Coche-Dequeant B, Lartigau E. Low-dose-rate interstitial brachytherapy boost for the treatment of anal canal cancers. Brachytherapy. 2017 Jan-Feb;16(1):230-235. doi: 10.1016/j.brachy.2016.07.007. Epub 2016 Sep 3.

Reference Type RESULT
PMID: 27600606 (View on PubMed)

Boukhelif W, Ferri-Molina M, Mazeron R, Maroun P, Duhamel-Oberlander AS, Dumas I, Martinetti F, Guemnie-Tafo A, Chargari C, Haie-Meder C. Interstitial pulsed-dose-rate brachytherapy for the treatment of squamous cell anal carcinoma: A retrospective single institution analysis. Brachytherapy. 2015 Jul-Aug;14(4):549-53. doi: 10.1016/j.brachy.2015.03.006. Epub 2015 Apr 29.

Reference Type RESULT
PMID: 25935731 (View on PubMed)

Other Identifiers

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BOOST-CA IPC 2017-016

Identifier Type: -

Identifier Source: org_study_id

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