Pediatric PET/MR Image Registry

NCT ID: NCT03458520

Last Updated: 2025-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-02-01

Study Completion Date

2025-12-31

Brief Summary

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The purpose of this study is to compare whole body magnetic resonance (MR) imaging, whole body positron emission tomography (PET)/MR imaging, and (if available) PET/Computed Tomography (CT) imaging for the diagnosis of tumors in children and young adults. Sensitivities, specificities and diagnostic accuracies of the different imaging modalities will be compared for significant differences.

Detailed Description

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Conditions

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Soft Tissue Lymphoma Osteosarcoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Image Registry

patients with proven solid tumors or newly diagnosed mass strongly suspected to represent a solid tumor will receive MR imaging, PET/MR imaging (and if available, PET/CT imaging)

PET/MR imaging

Intervention Type DIAGNOSTIC_TEST

undergo PET/MR imaging

MR imaging

Intervention Type DIAGNOSTIC_TEST

Undergo MR imaging

PET/CT imaging

Intervention Type DIAGNOSTIC_TEST

Undergo PET/CT imaging

Interventions

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PET/MR imaging

undergo PET/MR imaging

Intervention Type DIAGNOSTIC_TEST

MR imaging

Undergo MR imaging

Intervention Type DIAGNOSTIC_TEST

PET/CT imaging

Undergo PET/CT imaging

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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positron emission tomography magnetic resonance imaging computed tomography

Eligibility Criteria

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Inclusion Criteria

* Patients with proven solid tumors or newly diagnosed mass strongly suspected to represent a solid tumor.
* We might also include some patients with leukemia if there is concern for a focal lesion in any of their organs.
* Participant's parents (if participant is under 18) or the participant (if participant is 18 years or older) must willingly give written informed consent prior to any image transfer to the image registry.

Exclusion Criteria

* Patient has contraindications for MRI or PET/MR. This includes patients with cardiac pacemakers or intracranial vascular clips as well as patients with a blood glucose level \> 200 mg/dl.
* Lack of parental permission (if participant is younger than 18) or lack of informed consent (if participant is at least 18 years of age).
* Patient has a CNS primary tumor.
* Pregnant women and fetuses
Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Stanford University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Heike Daldrup-Link, MD

Role: PRINCIPAL_INVESTIGATOR

Stanford University

Locations

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Stanford University, School of Medicine

Palo Alto, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Anne Muehe

Role: CONTACT

650-720-8601

Facility Contacts

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Anne Muehe

Role: primary

650-720-8601

Other Identifiers

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IRB-44706

Identifier Type: -

Identifier Source: org_study_id

PEDSVAR0049

Identifier Type: OTHER

Identifier Source: secondary_id

5U24CA264298-04

Identifier Type: NIH

Identifier Source: secondary_id

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