Contribution of Narrow Band Imaging (NBI) for the Characterization of Scalloped Polyps (NBI POLYPES COLIQUES)

NCT ID: NCT03448653

Last Updated: 2024-11-29

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

314 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-09

Study Completion Date

2022-07-12

Brief Summary

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This prospective bicentric trial aims to evaluate the diagnostic performance of the characterization of scalloped polyps less than 20 millimeter in NBI (Narrow Band Imaging) in patients with screening colonoscopy.

The NBI is a so-called "virtual" electronic staining technique available on conventional OLYMPUS endoscopes without additional intervention.

The colonoscopy procedure for each patient will not be different from a conventional colonoscopy examination with excision of all polyps visualized and anatomopathological analysis, except for a short time of analysis in NBI for each polyp detected before excision to classify the polyp in existing endoscopic classifications (ie NICE classification for adenomatous polyps and WASP classification for festooned polyps).

Detailed Description

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Conditions

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Polyps of Colon

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Colonoscopy with NBI

Group Type EXPERIMENTAL

Colonoscopy with NBI

Intervention Type OTHER

Colonoscopy with NBI

Interventions

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Colonoscopy with NBI

Colonoscopy with NBI

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Major patient with a colonoscopy scheduled in one of the participating hospitals (CHD Vendée and CHU Nantes).
* Patient who agreed to participate in the study and gave his express consent
* Patient affiliated with a social security system or beneficiary of a scheme


* Patient with 1 or more polyps less than 20 mm observed during colonoscopy

Exclusion Criteria

* Patient with an emergency colonoscopy for ongoing digestive bleeding or occlusion symptoms
* Patient with chronic inflammatory bowel disease (IBD): Crohn's disease or unclassified colitis
* Patient with familial adenomatous polyposis
* Pregnant or lactating woman
* Minor patient
* Major patient under tutorship, curatorship, or deprived of liberty
* Patient unable to understand protocol and / or give express consent
* Patient not affiliated with a social security system or beneficiary of such a scheme
* Patient hospitalized or treated without their consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Departemental Vendee

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vincent MACE

Role: STUDY_DIRECTOR

Centre Hospitalier Départemental Vendée

Locations

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Centre Hospitalier Départemental Vendée

La Roche-sur-Yon, , France

Site Status

Centre Hospitalier Universitaire Nantes

Nantes, , France

Site Status

Countries

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France

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CHD010-17

Identifier Type: -

Identifier Source: org_study_id