Fournier's Gangrene and the Origin of the Infection as a Prognostic of Morbidity and Mortality, an Analysis of 121 Patients
NCT ID: NCT03443544
Last Updated: 2018-02-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
121 participants
OBSERVATIONAL
2017-11-01
2018-02-01
Brief Summary
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Fournier's gangrene it's a necrotizing infection of the genital area, with high morbidity and mortality. The site of infection its the origin of the necrotizing fasciitis. There are 4 well known origins of Fournier's gangrene: Testicular, Intestinal, Urinary and cutaneous, and its prognostic value has not been established yet, that's because the lack of case series with adequate number of patients. This is a retrospective study in which we evaluate the prognostic factors of every patient and its mortality compared with its origin area and multiple scores with their survival rates and hospital stay.
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Detailed Description
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To evaluate origins of Fournier's gangrene as a prognostic value in the morbidity and mortality.
Patients and methods:
This is a retrospective study where patients from a single hospital from 2007 to 2016 were included. They were categorized in 4 groups matching the origin of infection. In every group categorizing with the origin of infection and determined severity factors, days of hospital stay, Fournier's gangrene severity index and mortality. A statistic analysis will be done using lineal multivariable analysis.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Intestinal origin
Either perianal abcess or rectal carcinoma
Aggressive debridement
Aggressive debridement of the tissues undergoing fascitis
Testicular Origin
Complicated epididymitis with fascitis,
Aggressive debridement
Aggressive debridement of the tissues undergoing fascitis
Urinary Origin
From urinary tract infection or fistulae from urethral trauma
Aggressive debridement
Aggressive debridement of the tissues undergoing fascitis
Cutaneous Origin
mostly folliculitis, and skin infections
Aggressive debridement
Aggressive debridement of the tissues undergoing fascitis
Interventions
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Aggressive debridement
Aggressive debridement of the tissues undergoing fascitis
Eligibility Criteria
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Inclusion Criteria
* Fournier's Gangrene
* All patients treated with two antibiotics
* All patients undergone with aggressive debridement
Exclusion Criteria
* Not having Fournier's Gangrene
MALE
No
Sponsors
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Hospital Universitario Dr. Jose E. Gonzalez
OTHER
Responsible Party
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Adrián Gutiérrez González
Chief of department
Locations
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Hospital Universitario "Dr Jose Eleuterio Gonzalez"
Monterrey, , Mexico
Countries
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Other Identifiers
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UR16-00003
Identifier Type: -
Identifier Source: org_study_id
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