High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients

NCT ID: NCT03430258

Last Updated: 2018-02-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-03-01

Study Completion Date

2019-03-30

Brief Summary

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This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

Detailed Description

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This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

Conditions

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Blunt Thoracic Injury Lung Ultrasound Score

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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conventional oxygen therapy

oxygen was delivered by a nasal cannula or nonrebreather mask

Group Type PLACEBO_COMPARATOR

Conventional oxygen therapy

Intervention Type DEVICE

Conventional oxygen therapy

High-flow Nasal Cannula Oxygen Therapy

High-flow Nasal Cannula Oxygen Therapy

Group Type ACTIVE_COMPARATOR

high-flow nasal cannula

Intervention Type DEVICE

high flow of air with supplemental oxygen was delivered by an Optiflow cannula interface using an AIRVO 2 blower humidifier

Interventions

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high-flow nasal cannula

high flow of air with supplemental oxygen was delivered by an Optiflow cannula interface using an AIRVO 2 blower humidifier

Intervention Type DEVICE

Conventional oxygen therapy

Conventional oxygen therapy

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

\- The trauma registry was used to identify patients with moderate to severe blunt thoracic injury (abbreviated injury scale (AIS) chest score ≥3) admitted to the ICU

Exclusion Criteria

1. had intubation and used the mechanical ventilation within 2 hours
2. had the emergency surgerys within 2 hours
3. patients can not accessed by transthoracic lung ultrasound because of the sever aerodermectasia or pneumothorax
4. the Glasgow Coma Scale \<8
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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19850703

Identifier Type: -

Identifier Source: org_study_id

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