Trial Outcomes & Findings for Development, Feasibility and Acceptability of Fathers and Babies (FAB): A Pilot Study (NCT NCT03427528)

NCT ID: NCT03427528

Last Updated: 2022-07-18

Results Overview

Beck Depression Inventory-II (BDI-II) (Beck et al., 1988). The BDI-II was used to assess severity of depressive symptoms consistent with DSM-IV symptom criteria. The BDI-II is a 21-item survey, each item asks respondents to indicate on a scale ranging from 0 to 3 the extent to which they endorse different symptoms of depression over the past two weeks with higher scores indicating greater depression severity, with the highest score of 63. 0-10-considered normal 11-16 Mild mood disturbance 17-20 Borderline clinical depression 21-30 Moderate depression 31-40 Severe depression Over 40 Extreme depression.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

60 participants

Primary outcome timeframe

Baseline and Post Intervention at 3 and 6 months

Results posted on

2022-07-18

Participant Flow

We used a single group longitudinal pre-post design to evaluate study outcomes. Nine HV programs served as project partners and referral sites. These HV programs had been previously trained on MB and had prior experience delivering MB to perinatal women. HV programs participated in a training webinar with study investigators to review FAB implementation, study design and participant recruitment. We received 37 father-mother dyad referrals, of whom 30 (81%) were enrolled.

Participant milestones

Participant milestones
Measure
FAB Pilot Study (Father Participants)
Dyads including the home visiting client (Mom) and her partner (Father) will receive separate interventions. The inventions are complimentary and were implemented in parallel. Fathers received Fathers and Babies (FAB Intervention) while his partner (Mom) will receive MB 1-on-1 plus MB-TXT.
MB 1-on-1 Plus TEXT (Mother Participants)
Dyads including the HV client (Mom) and her partner (Father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel. HV clients (Mothers) received the Mothers and Babies with -Text Messages intervention (i.e., MB 1-on-1 plus MB-TXT) while her partner (Father) received FAB.
Overall Study
STARTED
30
30
Overall Study
COMPLETED
17
23
Overall Study
NOT COMPLETED
13
7

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Development, Feasibility and Acceptability of Fathers and Babies (FAB): A Pilot Study

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
FAB Pilot Study (Father Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
MB 1-on-1 Plus TEXT (Mother Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
Total
n=60 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
30 Participants
n=5 Participants
30 Participants
n=7 Participants
60 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Continuous
27.7 years
STANDARD_DEVIATION 6.0 • n=5 Participants
26.5 years
STANDARD_DEVIATION 5.5 • n=7 Participants
27.1 years
STANDARD_DEVIATION 5.6 • n=5 Participants
Sex: Female, Male
Female
0 Participants
n=5 Participants
30 Participants
n=7 Participants
30 Participants
n=5 Participants
Sex: Female, Male
Male
30 Participants
n=5 Participants
0 Participants
n=7 Participants
30 Participants
n=5 Participants
Race/Ethnicity, Customized
Black/African American
11 Participants
n=5 Participants
10 Participants
n=7 Participants
21 Participants
n=5 Participants
Race/Ethnicity, Customized
Hispanic/Latino
9 Participants
n=5 Participants
9 Participants
n=7 Participants
18 Participants
n=5 Participants
Race/Ethnicity, Customized
White/Caucasian
8 Participants
n=5 Participants
8 Participants
n=7 Participants
16 Participants
n=5 Participants
Race/Ethnicity, Customized
Other
2 Participants
n=5 Participants
3 Participants
n=7 Participants
5 Participants
n=5 Participants
Region of Enrollment
United States
30 Participants
n=5 Participants
30 Participants
n=7 Participants
60 Participants
n=5 Participants
Educational Attainment
< High school degree
3 Participants
n=5 Participants
3 Participants
n=7 Participants
6 Participants
n=5 Participants
Educational Attainment
High school degree/GED
12 Participants
n=5 Participants
6 Participants
n=7 Participants
18 Participants
n=5 Participants
Educational Attainment
Some college or beyond
15 Participants
n=5 Participants
21 Participants
n=7 Participants
36 Participants
n=5 Participants
Relationship Status
Married
8 Participants
n=5 Participants
8 Participants
n=7 Participants
16 Participants
n=5 Participants
Relationship Status
Engaged
5 Participants
n=5 Participants
5 Participants
n=7 Participants
10 Participants
n=5 Participants
Relationship Status
Single
10 Participants
n=5 Participants
10 Participants
n=7 Participants
20 Participants
n=5 Participants
Relationship Status
Living with partner, not married/engaged
7 Participants
n=5 Participants
7 Participants
n=7 Participants
14 Participants
n=5 Participants
Employment Status (N, %)
Not currently working
0 Participants
n=5 Participants
18 Participants
n=7 Participants
18 Participants
n=5 Participants
Employment Status (N, %)
Working part-time
5 Participants
n=5 Participants
7 Participants
n=7 Participants
12 Participants
n=5 Participants
Employment Status (N, %)
Working full-time
25 Participants
n=5 Participants
5 Participants
n=7 Participants
30 Participants
n=5 Participants
Prenatal enrollees
6 Participants
n=5 Participants
6 Participants
n=7 Participants
12 Participants
n=5 Participants
Postnatal enrollees
24 Participants
n=5 Participants
24 Participants
n=7 Participants
48 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Baseline and Post Intervention at 3 and 6 months

Population: Analysis included participants who completed assessments at all time points associated with an analysis.

Beck Depression Inventory-II (BDI-II) (Beck et al., 1988). The BDI-II was used to assess severity of depressive symptoms consistent with DSM-IV symptom criteria. The BDI-II is a 21-item survey, each item asks respondents to indicate on a scale ranging from 0 to 3 the extent to which they endorse different symptoms of depression over the past two weeks with higher scores indicating greater depression severity, with the highest score of 63. 0-10-considered normal 11-16 Mild mood disturbance 17-20 Borderline clinical depression 21-30 Moderate depression 31-40 Severe depression Over 40 Extreme depression.

Outcome measures

Outcome measures
Measure
FAB Pilot Study (Father Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
MB 1-on-1 Plus TEXT (Mother Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
Change in Depressive Symptoms
3 Months
4.5 score on a scale
Standard Deviation 4.6
8.4 score on a scale
Standard Deviation 9.5
Change in Depressive Symptoms
6 Months
3.6 score on a scale
Standard Deviation 5.1
8.3 score on a scale
Standard Deviation 8.4
Change in Depressive Symptoms
Baseline
6.5 score on a scale
Standard Deviation 6.6
9.7 score on a scale
Standard Deviation 8.1

PRIMARY outcome

Timeframe: Baseline and Post Intervention at 3 and 6 months

Population: Analysis was limited to individuals for whom we had complete data at the time points used for analysis.

Generalized Anxiety Disorder 7-item Scale (GAD-7) (Spitzer et al., 2006). The GAD-7 is a 7-item survey, each item asks respondents to indicate on a 4-point scale the extent to which they endorse different symptoms of anxiety over the past two weeks with higher scores indicating greater anxiety symptoms. The highest score is 21. Score 0-4: Minimal Anxiety Score 5-9: Mild Anxiety Score 10-14: Moderate Anxiety Score greater than 15: Severe Anxiety

Outcome measures

Outcome measures
Measure
FAB Pilot Study (Father Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
MB 1-on-1 Plus TEXT (Mother Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
Change in Anxiety
Baseline
4.1 score on a scale
Standard Deviation 4.5
6.8 score on a scale
Standard Deviation 5.5
Change in Anxiety
3 Months
3.2 score on a scale
Standard Deviation 3.4
6.2 score on a scale
Standard Deviation 51
Change in Anxiety
6 Months
2.8 score on a scale
Standard Deviation 3.2
6.3 score on a scale
Standard Deviation 4.8

PRIMARY outcome

Timeframe: Baseline and Post Intervention at 3 and 6 months

Population: Analysis was limited to individuals for whom we had complete data at the time points used for analysis.

Perceived Stress Scale 10-item Scale (PSS-10) (Cohen \& Williamson, 1988). The PSS-10 is a 10-item survey that asks respondents to indicate on a 5-point scale the extent to which they appraised certain situations as stressful over the past month, with higher scores indicating greater perceived stress. Individual scores on the PSS can range from 0 to 40 with higher scores indicating higher perceived stress. 0-13 are considered low stress Scores ranging from 14-26 are considered moderate stress Scores ranging from 27-40 are considered high perceived stress

Outcome measures

Outcome measures
Measure
FAB Pilot Study (Father Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
MB 1-on-1 Plus TEXT (Mother Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
Change in Perceived Stress
3-Month
12.6 score on a scale
Standard Deviation 7.1
16.9 score on a scale
Standard Deviation 7.4
Change in Perceived Stress
Baseline
14.9 score on a scale
Standard Deviation 7.6
20.4 score on a scale
Standard Deviation 9.1
Change in Perceived Stress
6-Month
10.9 score on a scale
Standard Deviation 9.1
16.8 score on a scale
Standard Deviation 6.8

SECONDARY outcome

Timeframe: Baseline and Post Intervention at 3 and 6 months

Population: Analysis was limited to individuals for whom we had complete data at the time points used for analysis.

Social Support Effectiveness Questionnaire (SSE-Q) (Rini et al., 2011). The SSE-Q is a 25-item survey that asks respondents to indicate the extent to which their partners provided different types of support in the past three months. The SSE-Q consists of subscales on task support, informational support, emotional support, and negative effects of support. For this study, we calculated a total social support score that summed these four subscales (range 0-80). High scores indicate more effective support. Full scale scores can range from 0 to 80, and each subscale can range from 0 to 20.

Outcome measures

Outcome measures
Measure
FAB Pilot Study (Father Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
MB 1-on-1 Plus TEXT (Mother Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
Change in Social Support Effectiveness
Baseline
60.9 score on a scale
Standard Deviation 14.3
48.9 score on a scale
Standard Deviation 11.6
Change in Social Support Effectiveness
3-Month
57.8 score on a scale
Standard Deviation 12.6
51.4 score on a scale
Standard Deviation 14.5
Change in Social Support Effectiveness
6-Month
59.3 score on a scale
Standard Deviation 13.7
52.2 score on a scale
Standard Deviation 12.2

SECONDARY outcome

Timeframe: Baseline and Post Intervention at 3 and 6 months

Population: Analysis was limited to individuals for whom we had complete data at the time points used for analysis.

The measure consists of 8 questions and asks respondents to indicate on a 5-point scale the extent to which they have received different types of instrumental support in the last month. Higher scores indicate greater support. We report on the count and percentage of individuals with high instrumental support at each time point.

Outcome measures

Outcome measures
Measure
FAB Pilot Study (Father Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
MB 1-on-1 Plus TEXT (Mother Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
Instrumental Social Support Support Survey (Cyranowski et al., 2013).
Baseline
9 Participants
4 Participants
Instrumental Social Support Support Survey (Cyranowski et al., 2013).
3-Month
6 Participants
8 Participants
Instrumental Social Support Support Survey (Cyranowski et al., 2013).
6-Month
9 Participants
9 Participants

SECONDARY outcome

Timeframe: Baseline and Post Intervention at 3 and 6 months

Population: NIH Toolbox Instrumental Support Support Survey. Each survey consists of 8 questions and asks respondents to indicate on a 5-point scale the extent to which they have received different types of instrumental and emotional support in the last month. Higher scores indicate greater support. Reported on percentage of participants with high levels of instrumental support at all time points.

NIH Toolbox Emotional Support Support Survey. The survey consists of 8 questions and asks respondents to indicate on a 5-point scale the extent to which they have received different types of emotional support in the last month. Higher scores indicate greater support. We report on the count and percentage of individuals with high emotional support at each time point.

Outcome measures

Outcome measures
Measure
FAB Pilot Study (Father Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
MB 1-on-1 Plus TEXT (Mother Participants)
n=30 Participants
Dyads including a HV client (mother) and her partner (father) will receive separate interventions. The inventions are complimentary and will be implemented in parallel.
Emotional Support Support (Cyranowski et al., 2013)
Baseline
9 Participants
7 Participants
Emotional Support Support (Cyranowski et al., 2013)
3-Month
6 Participants
9 Participants
Emotional Support Support (Cyranowski et al., 2013)
6-Month
8 Participants
5 Participants

Adverse Events

FAB Pilot Study (Father Participants)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

MB 1-on-1 Plus TEXT (Mother Participants)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Darius Tandon

Northwestern University, CCH

Phone: +1 312 503 3398

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place