Evaluation of Efficacy and Safety of SDN-037

NCT ID: NCT03426267

Last Updated: 2021-05-17

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

325 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-28

Study Completion Date

2020-03-05

Brief Summary

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The efficacy and safety of SDN-037 twice daily will be evaluated and compared with vehicle for the treatment of inflammation and pain associated with ocular surgery.

Detailed Description

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Conditions

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Inflammation and Pain Associated With Ocular Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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SDN-037

Group Type EXPERIMENTAL

SDN-037

Intervention Type DRUG

twice daily

vehicle

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

twice daily

Interventions

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SDN-037

twice daily

Intervention Type DRUG

Placebo

twice daily

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Be at least 2 years of age on the date of assent or 18 years of age at the date of consent
2. Be able and willing to follow study instructions and complete all required visits
3. Females of childbearing potential must not be pregnant (as confirmed by a negative urine pregnancy test
4. Able to self-instill the IP or have a caregiver available to instil all doses of the IP

Exclusion Criteria

1. Any known allergy or hypersensitivity to difluprednate therapy
2. An acute ocular infection (bacterial, viral or fungal) or active ocular inflammation in the study eye
3. Any active corneal pathology noted in the study eye
4. Currently suffering from alcohol and/or drug abuse
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sun Pharma Advanced Research Company Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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SPARC Site 13

Chandler, Arizona, United States

Site Status

SPARC Site 14

Mesa, Arizona, United States

Site Status

SPARC Site 11

Prescott, Arizona, United States

Site Status

SPARC Site 12

Sun City, Arizona, United States

Site Status

SPARC site 01

Fayetteville, Arkansas, United States

Site Status

SPARC Site 10

Santa Barbara, California, United States

Site Status

SPARC Site 08

Colorado Springs, Colorado, United States

Site Status

SPARC Site 06

Coral Springs, Florida, United States

Site Status

SPARC Site 18

Fort Myers, Florida, United States

Site Status

SPARC Site 16

Jacksonville, Florida, United States

Site Status

SPARC Site 07

Miami, Florida, United States

Site Status

SPARC Site 15

Paducah, Kentucky, United States

Site Status

SPARC Site 05

Saint Joseph, Michigan, United States

Site Status

SPARC Site 09

Henderson, Nevada, United States

Site Status

SPARC Site 03

Poughkeepsie, New York, United States

Site Status

SPARC Site 04

Winston-Salem, North Carolina, United States

Site Status

SPARC Site 17

Fargo, North Dakota, United States

Site Status

SPARC Site 19

Austin, Texas, United States

Site Status

SPARC Site 2

Mission, Texas, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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CLR_16_31

Identifier Type: -

Identifier Source: org_study_id

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