Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women

NCT ID: NCT03416010

Last Updated: 2025-03-18

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

299 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-03-05

Study Completion Date

2023-04-20

Brief Summary

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The overall purpose of this application is to evaluate the efficacy of an intervention designed to decrease health disparities in pregnant, emotionally distressed, minority women. This randomized controlled trial will test a six session (spaced over 18 weeks) cognitive behavioral skills building (CBSB) prenatal care intervention (specifically designed and based on prior research for pregnant minority women experiencing emotional distress) at three sites (Jacobi Medical Center, New York City and The Ohio State University Total Health and Wellness Clinic, and The Ohio State University Wexner Medical Center OB/GYN Columbus, Ohio.

Detailed Description

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A randomized controlled trial will test a cognitive behavioral skills building intervention (COPE-P) in Black and Hispanic women experiencing emotional distress in two sites (New York and Ohio) to determine if the intervention leads to better health behaviors, better psychosocial health (anxiety, stress, and depressive symptoms), and improved birth and post-natal outcomes in women experiencing emotional distress. Developing scalable prenatal interventions designed to improve birth outcomes as well as maternal physical and psychosocial health is essential to decrease health disparities in pregnant minority women.

Conditions

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Emotional Disturbances Depression Pregnancy Late Post-Partum Depression Anxiety Nutritional Deficiency

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

longitudinal, randomized block RCT with repeated measures
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Control

In addition to standard prenatal care the PregnancyPlus attention control group for 6 weeks will receive 1.5 hours of ACOG-designed patient education pamphlets. Material will include prenatal and post-partum education.. Dr. Gennaro will conduct the training of the attention control group midwives. The same protocol for assessing fidelity for COPE-P also will be used for assessing fidelity to the attention control intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Intervention

In addition to standard prenatal care the COPE-P intervention group will also receive 1.5 hours each week for 6 weeks the cognitive-behavior skills building program driven by CBT as the theoretical framework by health care providers trained in COPE-P by Dr. Melnyk. The content of the COPE program is driven by the literature review, the theoretical framework, previous studies of COPE interventions with mothers of preterm infants and prior work with pregnant minority women by our team.

Group Type ACTIVE_COMPARATOR

COPE-P

Intervention Type BEHAVIORAL

Session 1 ABCs (A=Antecedent or Activator event, B=Belief that follows the event, C=Consequence: how you feel and how you behave).

Session 2 self-esteem and positive self-talk, including ways to build self-esteem and the group provides examples of how to change unhealthy habits into healthy ones.

Session 3 stress/coping during pregnancy. Physical and emotional responses to stress are discussed along with healthy snacking and healthy ways to cope with typical stresses.

Session 4 planning, goal setting and the 4-step problem solving process. Session 5 dealing with emotions in healthy ways through positive thinking and effective communication.

Session 6 coping with stressful situations encountered during pregnancy while continuing to reinforce the thinking-feeling-behaving triangle.

Interventions

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COPE-P

Session 1 ABCs (A=Antecedent or Activator event, B=Belief that follows the event, C=Consequence: how you feel and how you behave).

Session 2 self-esteem and positive self-talk, including ways to build self-esteem and the group provides examples of how to change unhealthy habits into healthy ones.

Session 3 stress/coping during pregnancy. Physical and emotional responses to stress are discussed along with healthy snacking and healthy ways to cope with typical stresses.

Session 4 planning, goal setting and the 4-step problem solving process. Session 5 dealing with emotions in healthy ways through positive thinking and effective communication.

Session 6 coping with stressful situations encountered during pregnancy while continuing to reinforce the thinking-feeling-behaving triangle.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Pregnant women between the ages of 18-40 years old
* Pregnant women experiencing an uncomplicated singleton pregnancy of less than 19 weeks
* Self-identified as either Black or Hispanic
* Able to read and speak English.
* The child participants born to the participants will have their record accessed for data collection.

Exclusion Criteria

* Women with chronic medical conditions (e.g., hypertension, or diabetes), are currently receiving treatment or therapy for a psychiatric diagnosis, or have participated in this study with a prior pregnancy.
* Women with obstetrical complications, such as preeclampsia, gestational diabetes, or fetal abnormalities.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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National Institutes of Health (NIH)

NIH

Sponsor Role collaborator

New York University

OTHER

Sponsor Role collaborator

Jacobi Medical Center

OTHER

Sponsor Role collaborator

Boston College

OTHER

Sponsor Role collaborator

University of Arizona

OTHER

Sponsor Role collaborator

Drexel University

OTHER

Sponsor Role collaborator

National Institute on Minority Health and Health Disparities (NIMHD)

NIH

Sponsor Role collaborator

University of South Florida

OTHER

Sponsor Role collaborator

Ohio State University

OTHER

Sponsor Role lead

Responsible Party

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Bernadette Melnyk

Dean and Professor, College of Nursing Vice President of Health Promotion, Professor of Pediatrics and Psychiatry, College of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bernadette Melnyk, PhD

Role: PRINCIPAL_INVESTIGATOR

Ohio State University

Locations

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Jacobi Medical Center

The Bronx, New York, United States

Site Status

OSU Total Health and Wellness

Columbus, Ohio, United States

Site Status

OSUWMC OB/GYN Clinic

Columbus, Ohio, United States

Site Status

Countries

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United States

References

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Gennaro S, Melnyk BM, Szalacha LA, Gibeau AM, Hoying J, O'Connor CM, Cooper AR, Aviles MM. Effects of Two Group Prenatal Care Interventions on Mental Health: An RCT. Am J Prev Med. 2024 May;66(5):797-808. doi: 10.1016/j.amepre.2024.01.005. Epub 2024 Feb 5.

Reference Type DERIVED
PMID: 38323949 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan: Ohio Study Protocol

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Document Type: Study Protocol and Statistical Analysis Plan: New York Study Protocol

View Document

Document Type: Informed Consent Form: Ohio Informed Consent Form

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Document Type: Informed Consent Form: New York Informed Consent Form

View Document

Other Identifiers

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1R01MD012770-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

2017B0425

Identifier Type: -

Identifier Source: org_study_id

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