VBeam Prima for Treatment of Photoaged Facial Skin

NCT ID: NCT03383705

Last Updated: 2017-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-15

Study Completion Date

2018-11-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is an open-label, single-center study. Subjects in this study will receive up to four (4) facial treatments at 4-6 (±1) weeks interval, with the VBeam Prima device according to the study protocol. Subjects will return for follow-up (FU) visits at the clinic at 1 and 3 months following the last treatment.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Photoaged Facial Skin

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Photoaged Skin

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Treatment arm

Group Type EXPERIMENTAL

VBeam Prima

Intervention Type DEVICE

Up to four treatments will be performed every 4-6 (±1) weeks.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

VBeam Prima

Up to four treatments will be performed every 4-6 (±1) weeks.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Healthy Male or Female at least 18 years of age
2. Photoaged facial skin with clinically visible background erythema, telangiectasia, or pigmented lesions
3. Fitzpatrick Elastosis Score 2-9
4. Fitzpatrick Skin Type I - VI
5. Able to read, understand and sign the Informed Consent Form
6. Willing and able to adhere to the treatment and follow-up schedule and post-treatment care instructions
7. Willing to have limited sun exposure for the duration of the study, including the follow-up period
8. Willing to have photographs taken of the treated area which will be used, de-identified, in evaluations and may be used, de-identified, in presentations and/or publications
9. For female candidates - subject must be post-menopausal, or surgically sterilized, or using a medically acceptable form of birth control during the entire course of the study.

Exclusion Criteria

1. Pregnant or planning to become pregnant during the study duration.
2. Implant in the treated area (such as metal plates or screws) or an injected chemical substance.
3. Known collagen (connective tissue) disorder, vascular disease (i.e. saphenous reflux), scleroderma or other autoimmune disease (i.e. rheumatoid arthritis, lupus).
4. History of diseases stimulated by heat or sun exposure, such as recurrent Herpes Simplex in the treated area, unless treatment is conducted following a prophylactic regimen.
5. History of immunosuppression/immune deficiency disorders (including HIV infection or AIDS) or currently using immunosuppressive medications.
6. Undergoing any form of treatment for active cancer, or having a history of skin cancer or any other cancer in the areas to be treated, including actinic keratosis, presence of malignant or pre-malignant pigmented lesions.
7. Significant concurrent illness, such as such as cardiac disorders, diabetes (type I or II), or pertinent neurological disorders.
8. Infection or are suffering from a current or a history of significant skin conditions in the treated area and/or inflammatory skin conditions, including, but not limited to: photodermatoses, psoriasis, eczema, rash, severe open wound stage rosacea, open cuts or scrapes and active cold sores or herpes sores prior to study treatment or during the study treatment course.
9. Anticoagulative or thromboembolic condition or taking anticoagulation medications one week prior to and during the treatment course (to allow inclusion, temporary cessation of use might be requested as per the subject's physician discretion).
10. Use of aspirin or pain relievers from the ibuprofen family (e.g., Motrin®, Advil®, or Naprosyn®) on a regular basis or would be taking any of these pain relievers one week before and after each study treatment session.
11. History of keloid scarring or of abnormal wound healing.
12. Photosensitivity to the device's laser wavelengths, history of ingesting medications known to induce photosensitivity, or history of seizure disorders due to light.
13. Surgical, light-based therapy or RF procedures in the treatment area within 3 months of treatment or during the study.
14. Any other surgery in the treated area within 3 months of treatment (or more if skin has not healed completely) or during the study.
15. Tattoo or permanent make-up in the treated area.
16. Systemica use of retinoids (i.e. Retin-A®, Accutane®) or antioxidants (i.e. Restylane®, Strivectin®) within 2 months of study treatment or during the study.
17. Excessive tan in areas to be treated or unable/unlikely to refrain from tanning during the study.
18. Participation in a study of another device or drug within three months prior to enrollment or during the study.
19. As per the Investigator's discretion, any physical or mental condition which might make it unsafe for the subject to participate in this study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Syneron Medical

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Dermatology, Laser & Vein Specialists of the Carolinas

Charlotte, North Carolina, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Gilly Munavalli, MD

Role: CONTACT

Phone: (704) 375-6766

Email: [email protected]

Cindy Tucker, RN-C

Role: CONTACT

Phone: (704) 375-6766

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Cindy Tucker, RN-C

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

DHF24491

Identifier Type: -

Identifier Source: org_study_id