Stitch Closure of PFO and Septal Repair

NCT ID: NCT03373929

Last Updated: 2017-12-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

250 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-20

Study Completion Date

2022-11-20

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of the STITCH study is to evaluate closure rates of clinically relevant septal defects, including patent foramen ovale (PFO), Atrial Septal Defects (ASD - less than 1 cm with redundant septal tissue), trans septal puncture sites, repair of Atrial Septal Aneurysm (ASA) and rate of recurrent neurologic embolic events in patients with cryptogenic stroke and PFO.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Foramen Ovale, Patent Septal Defect, Atrial Septal Defect, Heart

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Non-randomized, single-center, observational study
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PFO Closure Rate

Evaluate closure rate of clinically relevant septal defects including PFO, ASD (less than 1 cm with redundant septal tissue), trans septal puncture sites, repair of ASA (when an appropriate PFO or small ASD defect is present) and rate of recurrent neurologic embolic event in patients with cryptogenic stroke and PFO

Group Type OTHER

PFO Closure Rate

Intervention Type DEVICE

Suture Mediated PFO Closure and Septal Repair

Published PFO Device Closure

Intervention Type DEVICE

Suture Mediated PFO Closure and Septal Repair

Published PFO Device Closure

Compare PFO closure rate and safety of closure of septal occluders in published PFO clinical trials.

Group Type OTHER

PFO Closure Rate

Intervention Type DEVICE

Suture Mediated PFO Closure and Septal Repair

Published PFO Device Closure

Intervention Type DEVICE

Suture Mediated PFO Closure and Septal Repair

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

PFO Closure Rate

Suture Mediated PFO Closure and Septal Repair

Intervention Type DEVICE

Published PFO Device Closure

Suture Mediated PFO Closure and Septal Repair

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* PFO
* ASD (less than 1 cm with redundant septal tissue)
* Trans Septal Puncture Sites
* ASA (when an appropriate PFO or small ASD defect is present)
* Stroke
* Trans ischemic Attack (TIA)
* Platypnea Orthodeoxia Syndrome
* Decompression Illness

Exclusion Criteria

* Patients under 18 and over 65
* Patients who are not fluent in English
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

HeartStitch.Com

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

James Thompson, MD

Interventional Cardiologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

James Thompson, MD

Role: PRINCIPAL_INVESTIGATOR

Inova Cardiovascular Institute

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Inova Cardiovascular Institute

Falls Church, Virginia, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

17-2871

Identifier Type: -

Identifier Source: org_study_id