Trial Outcomes & Findings for Impact of the Inspiratory Cortical Control on the Outcome of the Ventilatory Weaning Test in Patients Intubated in Resuscitation (NCT NCT03372252)

Results Overview

Amplitude in microvolts of the inspiratory premotor potentials measured during the first 15 minutes of the artificial noses breathing test in patients who successfully passed their ventilatory withdrawal and in patients who failed their withdrawal.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

70 participants

Primary outcome timeframe

Fifteen minutes

Results posted on

2026-01-07

Participant Flow

70 patients included but 62 patients could have been analyzed for technical maters

Participant milestones

Participant milestones
Measure	SBT Success 45 patients (73%) succeded the Spontaneous breathing trial	SBT Failure 17 patients (27%) failed the Spontaneous breathing trial
Overall Study STARTED	45	17
Overall Study COMPLETED	45	17
Overall Study NOT COMPLETED	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	SBT Success n=45 Participants 45 patients (73%) succeded the Spontaneous breathing trial	SBT Failure n=17 Participants 17 patients (27%) failed the Spontaneous breathing trial	Total n=62 Participants Total of all reporting groups
Age, Continuous	60 years n=45 Participants	70 years n=17 Participants	63 years n=62 Participants
Sex: Female, Male Female	20 Participants n=45 Participants	5 Participants n=17 Participants	25 Participants n=62 Participants
Sex: Female, Male Male	25 Participants n=45 Participants	12 Participants n=17 Participants	37 Participants n=62 Participants
Race and Ethnicity Not Collected	—	—	0 Participants Race and Ethnicity were not collected from any participant.
Body mass index	30 kg/m² n=45 Participants	32 kg/m² n=17 Participants	31 kg/m² n=62 Participants

PRIMARY outcome

Timeframe: Fifteen minutes

Amplitude in microvolts of the inspiratory premotor potentials measured during the first 15 minutes of the artificial noses breathing test in patients who successfully passed their ventilatory withdrawal and in patients who failed their withdrawal.

Outcome measures

Outcome measures
Measure	SBT Success n=45 Participants 45 patients (73%) succeded the Spontaneous breathing trial	SBT Failure n=17 Participants 17 patients (27%) failed the Spontaneous breathing trial
Magnitude of Inspiratory Premotor Potentials	1.2 µV Interval 0.5 to 2.0	2.1 µV Interval 1.7 to 2.9

Adverse Events

SBT Success

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

SBT Failure

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr RAULT Christophe

CHU de Poitiers

Phone: 0549445348

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place