The Effects of Radium-223 Dichloride Therapy on Radionuclide Bone Scan Lesions.

NCT ID: NCT03368989

Last Updated: 2019-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

21 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-02-11

Study Completion Date

2017-02-07

Brief Summary

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To describe the changes seen on bone scan and correlate them with changes in relative chemical biomarkers, patient's functional status and level of pain.

Detailed Description

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Conditions

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Bony Metastases From Castrate Refractory Prostate Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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treatment with radium-223 Dichloride (Xofigo)

Radium-223 dichloride

Intervention Type DRUG

Previously known as Alpharadin, Radium-223 dichloride is a calcium-mimetic, alpha emitting radiopharmaceutical, which introduces double-stranded DNA breaks in metastatic cancer cells.

Interventions

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Radium-223 dichloride

Previously known as Alpharadin, Radium-223 dichloride is a calcium-mimetic, alpha emitting radiopharmaceutical, which introduces double-stranded DNA breaks in metastatic cancer cells.

Intervention Type DRUG

Other Intervention Names

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Xofigo

Eligibility Criteria

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Inclusion Criteria

* Prostate cancer patients scheduled for treatment with Radium-223.

Exclusion Criteria

* Patients not completing their treatment regimen for any reason
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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The University of Texas Health Science Center, Houston

OTHER

Sponsor Role lead

Responsible Party

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Isis W Gayed

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Isis W Gayed, MD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Locations

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The University of Texas Health Science Center at Houston

Houston, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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HSC-MS-14-0113

Identifier Type: -

Identifier Source: org_study_id

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