Trial Outcomes & Findings for Perforator Vein Injection for Symptomatic Venous Disease (NCT NCT03363633)

NCT ID: NCT03363633

Last Updated: 2018-02-23

Results Overview

Change in wound size, reported in square centimeters

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

12 participants

Primary outcome timeframe

12 months

Results posted on

2018-02-23

Participant Flow

The Responsible Party is no longer at University of Pittsburgh and has confirmed that the study data were lost. The only information available is the study was terminated for recruitment difficulty following enrollment of 12 participants overall, with no breakdown per study arm (source: final report submitted to the IRB).

Participant milestones

Participant milestones
Measure
All Arms
Participants were randomized to either compression stockings or perforator vein injection with sodium tetradecyl sulfate, plus compression stockings.
Overall Study
STARTED
12
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
12

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

See note in Baseline Analysis Population Description

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: 12 months

Population: The Responsible Party is no longer at University of Pittsburgh and has confirmed that the study data were lost. The only information available is the study was terminated for recruitment difficulty following enrollment of 12 participants overall, with no breakdown per study arm (source: final report submitted to the IRB).

Change in wound size, reported in square centimeters

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 12 months

Population: The Responsible Party is no longer at University of Pittsburgh and has confirmed that the study data were lost. The only information available is the study was terminated for recruitment difficulty following enrollment of 12 participants overall, with no breakdown per study arm (source: final report submitted to the IRB).

The VCSS includes nine criteria of chronic venous disease, each graded from 0 to 3 (0=absent, 1=mild, 2=moderate, 3=severe). Up to three points may be added for differences in background conservative therapy (compression and elevation). The scores are then added, with a maximum score of 30.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 12 months

Population: The Responsible Party is no longer at University of Pittsburgh and has confirmed that the study data were lost. The only information available is the study was terminated for recruitment difficulty following enrollment of 12 participants overall, with no breakdown per study arm (source: final report submitted to the IRB).

Number of participants experiencing venous thromboses from injections

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 12 months

Population: The Responsible Party is no longer at University of Pittsburgh and has confirmed that the study data were lost. The only information available is the study was terminated for recruitment difficulty following enrollment of 12 participants overall, with no breakdown per study arm (source: final report submitted to the IRB).

Number of participants who use compression therapy

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 12 months

Population: The Responsible Party is no longer at University of Pittsburgh and has confirmed that the study data were lost. The only information available is the study was terminated for recruitment difficulty following enrollment of 12 participants overall, with no breakdown per study arm (source: final report submitted to the IRB).

Number of participants with ulcers that reopen after initial closure

Outcome measures

Outcome data not reported

Adverse Events

All Arms

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Ellen D. Dillavou, MD, FACS

Duke University Medical Center

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place