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Night Myopia and Dark Focus of Accommodation

NCT ID: NCT03358550

Last Updated: 2017-11-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

39 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-02-02

Study Completion Date

2017-03-23

Brief Summary

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Shifts in accommodation at decreasing luminance levels are considered as principle cause for night myopia. Previous studies with laser optometers quantified the dark focus of accommodation up to 3 D. In addition to the measurement of dark focus, the aim of this study was to investigate the influence of an imaginary target at finite distances on the state of accommodation at scotopic luminance.

Detailed Description

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Accommodation was measured by using an open-field autorefractor (WAM 5500, GRAND SEIKO). Full corrected right eyes of 39 subjects aged from 18 to 40 years were investigated in this randomized, cross-sectional study. Accommodation measurements in photopic luminance were taken for 6 m of empty field and for optotype fixation at 2 m, 1 m and 0.5 m. At scotopic luminance, dark focus of accommodation was examined directly after darkening and after 10 min of dark adaptation. After adaptation, subjects had to visualize imaginary targets in the four distances while accommodation was measured.

Conditions

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Dark Focus of Accommodation

Keywords

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accommodation dark focus night myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Sequence of tests was randomized. It is no multi-arm study.

Study Groups

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Accommodation in scotopic luminance

Group Type EXPERIMENTAL

Accommodation Measurement

Intervention Type DIAGNOSTIC_TEST

Accommodation was measured for different distances and light conditions.

Interventions

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Accommodation Measurement

Accommodation was measured for different distances and light conditions.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* age 18 - 44
* visual acuity at least 0.8 (5/6)

Exclusion Criteria

* medication with an impact on the visual system
* visual disease or disease with an impact on the visual system
* pregnancy or other hormonal variances
* drug usage
* overfatigue at the period of investigation
* mental handicap
Minimum Eligible Age

22 Years

Maximum Eligible Age

39 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Applied Sciences Jena

OTHER

Sponsor Role lead

Responsible Party

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Philipp Hessler

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Philipp Hessler, M.Sc.

Role: PRINCIPAL_INVESTIGATOR

University of Applied Sciences Jena

Locations

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University of Applied Sciences

Jena, Thuringia, Germany

Site Status

Countries

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Germany

Other Identifiers

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UASJena

Identifier Type: -

Identifier Source: org_study_id