Preoperative Corneal Thickness and Postoperative Visual Outcomes After Posterior Lamellar Corneal Transplant

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

113 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-10-01

Study Completion Date

2017-05-30

Brief Summary

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To evaluate the impact of preoperative corneal thickness on visual outcomes following Descemet's stripping endothelial keratoplasty (DSAEK) or Descemet membrane endothelial keratoplasty (DMEK)

Detailed Description

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Patients underwent DSAEK or DMEK for endothelial dysfunction, from October 2013 to November 2016. Patients aged \> 18 years and with an indication for posterior lamellar graft surgery, such as Fuchs dystrophy, were included. Exclusion criteria included a history of penetrating keratoplasty in the study eye and a need for a penetrating keratoplasty following endothelial graft failure. Visual acuity, central corneal thickness (CCT) and graft thickness were measured preoperatively, and at postoperative day 7 and months 1, 3 and 6.

Conditions

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Corneal Changes of Membranes

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Clinically indicated need for posterior lamellar graft surgery (DSAEK or DMEK) such as:

* Fuchs dystrophy,
* pseudophakic bullous decompensation
* or other endothelial dysfunction corneal

Exclusion Criteria

* were a history of penetrating keratoplasty in the indicated eye
* the technical inability of preoperative CCT measurement
* the need for a penetrating keratoplasty following endothelial graft failure
* severe postoperative complications resulting in unquantifiable visual acuity

Eligible Sex

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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2016-07Obs-CHRMT

Identifier Type: -

Identifier Source: org_study_id