Early-onset Pneumonia After Out-of-hospital Cardiac Arrest

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

240 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-10-03

Study Completion Date

2018-07-31

Brief Summary

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Early-onset pneumonia after out-of-hospital cardiac arrest is frequent. An association between early-onset pneumonia and an increase in morbidity has been reported in this population. The diagnosis of early-onset pneumonia inpatients with out-of-hospital cardiac arrest may be challenging as diagnosis criteria are unspecific in this setting. On the other hand some studies have reported an association between early antibiotics and better prognosis in patients with out-of-hospital cardiac arrest suggesting that early diagnosis and treatment of pneumonia would benefit to patients. Nonetheless, adminitration of antibiotics to any patients with out-of-hospital cardiac arrest would expose to antibiotic patients without infection and woould participate to increase in antibiotic resistance.

Therefore, the PP-ACR study aims to evaluate the impact of a diagnosis algorithm including blinded sampling protected brushes on early-onset pneumonia treatment and patient prognosis after out-of-hospital cardiac arrest.

Detailed Description

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This study is a single centre observational study with a before - after design.

Conditions

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Out-of-Hospital Cardiac Arrest

Keywords

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early onset pneumonia out-of-hospital cardiac arrest prognosis antibiotic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* patients admitted for out-of-hospital cardiac arrest and treated with hypothermia

Exclusion Criteria

* age less than 18
* consent withdrawal

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHRU de Brest

Brest, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Cecile Aubron, MD,PhD

Role: CONTACT

Email: [email protected]

Facility Contacts

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Cécile aubron

Role: primary

References

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Lemee P, Chapalain X, Bailly P, Sparrow RL, Jean-Michel V, Prat G, Renault A, Tonnelier JM, Aubron C. PROACTIVE SCREENING ALGORITHM FOR EARLY-ONSET PNEUMONIA IN PATIENTS WITH OUT-OF-HOSPITAL CARDIAC ARREST: A BEFORE-AFTER IMPLEMENTATION STUDY. Shock. 2024 Jul 1;62(1):13-19. doi: 10.1097/SHK.0000000000002347. Epub 2024 Mar 25.

Reference Type DERIVED

PMID: 38661180 (View on PubMed)

Other Identifiers

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PP-ACR

Identifier Type: -

Identifier Source: org_study_id