Effect of Intraoperative IV Ketamine on Postoperative Morphine Consumption During Intestinal Surgery
NCT ID: NCT03344393
Last Updated: 2017-11-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
60 participants
INTERVENTIONAL
2017-12-01
2019-03-01
Brief Summary
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Detailed Description
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II- Group C (control): 30 patients will receive intraoperative intravenous normal saline infusion.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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ketamine hydrochloride
intravenous ketamine infusion in the intraoperative period
Ketamine Hydrochloride
intravenous ketamine infusion intraoperatively
normal saline
intravenous normal saline infusion in the intraoperative period
Normal saline
intravenous normal saline infusion intraoperatively
Interventions
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Ketamine Hydrochloride
intravenous ketamine infusion intraoperatively
Normal saline
intravenous normal saline infusion intraoperatively
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients age above 18 years old.
* Patients scheduled for intestinal surgery.
Exclusion Criteria
* Patients with known allergy to ketamine or morphine.
* Patients with significant hepatic dysfunction.
* Patients with severe renal disease.
* Significant Heart disease.
* Patients with chronic pain.
* Regular use analgesics, antidepressants or opioids in last 2 months.
* Any known convulsive disorder.
* Morbid obesity (BMI\>35).
* Patients with autoimmune disease
* Patients on corticosteroid therapy
* Pregnancy.
* Breast feeding.
* Woman under hormonal treatment.
* Oral disease.
18 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Mohamed galal aly
Assistant Professor
Central Contacts
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References
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Arikan M, Aslan B, Arikan O, Horasanli E, But A. Comparison of the effects of magnesium and ketamine on postoperative pain and morphine consumption. A double-blind randomized controlled clinical study. Acta Cir Bras. 2016 Jan;31(1):67-73. doi: 10.1590/S0102-865020160010000010.
Other Identifiers
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17200147
Identifier Type: -
Identifier Source: org_study_id