Incomplete Total Body Protein Recovery in Adolescent Patients With Anorexia Nervosa
NCT ID: NCT03334032
Last Updated: 2017-11-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
154 participants
OBSERVATIONAL
2004-07-31
2010-07-31
Brief Summary
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Detailed Description
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Objective: The study intended to analyze predictors of protein status, including exercise status, in adolescents with AN, and to investigate whether weight gain would replete body protein deficits.
Methods: The investigators assessed TBPr in a longitudinal, observational study as height-adjusted nitrogen index (NI) using in-vivo neutron activation analysis in adolescents with AN at the commencement of refeeding (T0), as well as seven months thereafter (T1), and in age-matched normal weight controls. Lean tissue and fat mass were assessed with Dual-Energy X-Ray Absorptiometry (DXA). BMI, BMI-SDS and lean tissue mass were tested as predictors of protein status using Receiver Operating Characteristic (ROC) analysis.
Conditions
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Keywords
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Inpatient treatment for Anorexia nervosa
Adolescents with anorexia nervosa assessed
1. at baseline: on admission to inpatient treatment
2. at follow-up: 6 months after admission on outpatient basis
Inpatient treatment for Anorexia nervosa
Nutritional rehabilitation in a clinic with specialized eating disorder service
Controls
Adolescent healthy and normal weight controls (matched for gender and age), assessed at one point of time
No interventions assigned to this group
Interventions
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Inpatient treatment for Anorexia nervosa
Nutritional rehabilitation in a clinic with specialized eating disorder service
Eligibility Criteria
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Inclusion Criteria
* aged 12 - 19 years
* female gender
Exclusion Criteria
Controls:
* no known disease
* normal weight
12 Years
19 Years
FEMALE
Yes
Sponsors
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University of Sydney
OTHER
Charite University, Berlin, Germany
OTHER
Responsible Party
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Dr. Verena Haas
Principle Investigator, Clinical Researcher
Principal Investigators
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Michael R Kohn, Prof.
Role: PRINCIPAL_INVESTIGATOR
University of Sydney
Other Identifiers
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TBN in AN
Identifier Type: -
Identifier Source: org_study_id