Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
26 participants
INTERVENTIONAL
2017-02-13
2017-03-27
Brief Summary
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Glucagon-like peptide 1 (GLP-1) is involved in body weight maintenance. Beside energy balance it is also involved in glucose homeostasis. Functional deficit in GLP-1 facilitates obesity. We investigated the link between the concentration of incretin hormones and glucose homeostasis, metabolic complications and the distribution of body composition in obese women with PCOS.
Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
SCREENING
NONE
Study Groups
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NGT
NGT - normal glucose tolerance. Women with PCOS and normal glucose tolerance
oral glucose tolerance test
GLP1 response to oral glucose load during oral glucose tolerance test was assessed.
IGH
IGH - impaired glucose homeostasis Women with PCOS and impaired glucose homeostasis - that means impaired fasting glucose or impaired glucose tolerance.
oral glucose tolerance test
GLP1 response to oral glucose load during oral glucose tolerance test was assessed.
Interventions
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oral glucose tolerance test
GLP1 response to oral glucose load during oral glucose tolerance test was assessed.
Eligibility Criteria
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Inclusion Criteria
* polycystic ovary sindrome (NICHD criteria)
* BMI of 30 kg/m2 or higher
Exclusion Criteria
* Cushing's syndrome or congenital (non-classic) adrenal hyperplasia
* personal or family history of MEN 2
* the use of medications known or suspected to affect reproductive or metabolic functions
* the use of statins within 90 days prior to study entery
18 Years
50 Years
FEMALE
No
Sponsors
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University Medical Centre Ljubljana
OTHER
Responsible Party
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Andrej Janez
MD PhD
Principal Investigators
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Andrej Janez, MD PhD
Role: STUDY_CHAIR
University Medical Centre Ljubljana
Locations
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UMC Ljubljana
Ljubljana, , Slovenia
Countries
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Other Identifiers
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IGH PCOS and inkretins
Identifier Type: -
Identifier Source: org_study_id