The Role of Transanal Tube Drainage as A Mean of Prevention of Anastomotic Leakage Anastomotic Leakage

NCT ID: NCT03325361

Last Updated: 2017-10-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-31

Study Completion Date

2018-06-30

Brief Summary

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Anastomotic leakage (AL) is considered the commonest major complication after surgery for rectal cancer. Transanal tube drainage role in the prevention of AL is still debatable.

Detailed Description

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Patients who underwent low or ultralow anterior resection for rectal cancer were enrolled between 01/2015 and 06/2017. A de-Pezzer catheter was placed transanally after the creation of the anastomosis, secured to the buttocks, and connected to a urine bag to allow monitoring the amount and the color of the drainage. The catheter was removed on the 3rd day postoperative if the volume collected was insignificant.

Patients were followed-up on the ward and then in the outpatient's department at two weeks, and one month postoperative. Patients who were suspected to have AL underwent CT with rectal contrast to assess the integrity of the anastomosis. The primary outcome was the incidence of AL. We adopted the definition published by the International Study Group of Rectal Cancer.

Conditions

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Rectal Cancer Rectal Neoplasms Anastomotic Leak

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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TD

Group Type EXPERIMENTAL

Tube drain insertion

Intervention Type OTHER

A de-Pezzer catheter was placed transanally after the creation of the anastomosis, secured to the buttocks, and connected to a urine bag to allow monitoring the amount and the color of the drainage. The catheter was removed on the 3rd day postoperative if the volume collected was insignificant.

NTD

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Tube drain insertion

A de-Pezzer catheter was placed transanally after the creation of the anastomosis, secured to the buttocks, and connected to a urine bag to allow monitoring the amount and the color of the drainage. The catheter was removed on the 3rd day postoperative if the volume collected was insignificant.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Low or ultralow anterior resection with primary anastomosis for biopsy-proven primary rectal cancer

Exclusion Criteria

* No anastomosis
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Rome Tor Vergata

OTHER

Sponsor Role lead

Responsible Party

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Pierpaolo Sileri

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Policlinico Tor Vergata Hospital

Rome, RM, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Pierpaolo Sileri, PhD

Role: CONTACT

Phone: 3209353441

Email: [email protected]

Mostafa Shalaby, PhD

Role: CONTACT

Email: [email protected]

Facility Contacts

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Pierpaolo Sileri

Role: primary

Other Identifiers

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Transanal Tube Drainage

Identifier Type: -

Identifier Source: org_study_id