Effect of Clomiphene Citrate on Uterine Blood Fow in Women With Unexplained Delayed Conception

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-10-01

Study Completion Date

2016-10-30

Brief Summary

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In a prospective observational study at a university teaching hospital, blood flow indices and serum hormone levels were compared between spontaneous and stimulated cycles in the same group of 50 patients with unexplained delayed conception.

Detailed Description

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In a prospective observational study at a university teaching hospital, the mid-luteal (peri-implantation) endometrial thickness and volume, uterine artery pulsatility index (PI) and resistance index (RI), endometrial and subendometrial vascularization index, flow index, and vascularization flow index, and serum estradiol and progesterone levels were compared between spontaneous and clomiphene citrate stimulated cycles in the same group of 50 patients with unexplained infertility.

Conditions

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Infertility, Female

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

PROSPECTIVE

Interventions

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Vascularization indices observation

The mid-luteal endometrial thickness and volume, uterine vascularization indices of uterine artery pulsatility index and resistance index, endometrial and subendometrial vascularization index, flow index, and vascularization flow index, and serum estradiol and progesterone levels were calculated in spontaneous then stimulated cycles in the same group of infertile patients

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Unexplained infertility
* Body mass index less than 30
* Regular menstruation
* Normal pelvic examination and ultrasonography

Exclusion Criteria

* History of pelvic operations including cesarean section
* History of pelvic inflammatory disease
* Endometriosis
* Pelvic pathology including uterine fibroids
* General disease or medication that could potentially affect pelvic blood flow
* Smoking

Minimum Eligible Age

25 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Responsible Party

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Eman Omran

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Eman Omran, M.D.

Role: PRINCIPAL_INVESTIGATOR

Cairo University

Locations

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Department of Obstetrics and Gynecology, Kasr Al-Ainy hospital, Cairo University

Cairo, Greater Cairo, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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4588

Identifier Type: -

Identifier Source: org_study_id