Pilot Study on Weight Loss in Guinea Bissau

NCT ID: NCT03316742

Last Updated: 2022-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2020-12-31

Study Completion Date

2021-01-31

Brief Summary

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The purpose of this study is to test two versions a weight loss program potentially suitable for implementation in Africa. A successful method would have widespread application in low-income countries, with the potential to improve world health.

Detailed Description

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Specific Aim 1 is to conduct a 3-4 month pilot study randomizing participants to two versions of a weight loss program. The program will be implemented in a convenience sample of overweight and obese adults living in Guinea-Bissau and measure changes in body weight loss (primary outcome), adherence to program recommendations including recommended food patterns, blood pressure, eating behavior, physical activity and mood (secondary outcomes). The data will be used to refine the weight loss program and conduct power calculations for a future trial.

Specific Aim 2 is to analyze associations between weight loss, participant demographics and program metrics, to explore reasons for differences in weight loss between participants. Factors to be tested include participant BMI, gender and age, as well as adherence to meal portion recommendations, use of sugar-sweetened beverages and provided foods, and physical activity.

Conditions

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Overweight and Obesity Weight Loss

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intervention 1

Participants randomized to intervention 1 will complete baseline and endline outcomes and participate in version 1 of a weight loss program. Each participant will attend twelve one hour classes discussing weight loss adherence in addition to barriers experienced. Changes in weight will be recorded throughout the study.

Group Type EXPERIMENTAL

Intervention 1

Intervention Type COMBINATION_PRODUCT

Intervention 1 includes providing participants with a high fiber food product, protein source, high intensity sweetener and adult multivitamin.

Intervention 2

Participants randomized to intervention 2 will complete baseline and endline outcomes and participate in version 2 of a weight loss program. Each participant will attend 12 one hour classes discussing weight loss adherence in addition to barriers experienced. Changes in weight will be recorded throughout the study.

Group Type EXPERIMENTAL

Intervention 2

Intervention Type COMBINATION_PRODUCT

Intervention 2 includes providing participants with an alternative dietary fiber source, milk protein, high intensitysweetener and adult multivitamin.

Interventions

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Intervention 1

Intervention 1 includes providing participants with a high fiber food product, protein source, high intensity sweetener and adult multivitamin.

Intervention Type COMBINATION_PRODUCT

Intervention 2

Intervention 2 includes providing participants with an alternative dietary fiber source, milk protein, high intensitysweetener and adult multivitamin.

Intervention Type COMBINATION_PRODUCT

Eligibility Criteria

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Inclusion Criteria

* Men and women who are overweight or obese (BMI ≥25 kg/m2).
* Want to lose weight, want to enroll in the study and are willing to sign the informed consent form.
* Anticipate being able to meet the study requirements for food habits and study meetings, and anticipate remaining in Bissau for the study duration.
* Between the ages of 20 to 65 years.
* Non-pregnant women, and those who do not intend on becoming pregnant during the course of the study.
* A doctor or nurse has signed a note approving participant in the weight loss intervention after seeing a copy of the handout with title "Instructions for Bissau Weight Loss Pilot Project", and a copy of his/her approval is given to the research staff.

Exclusion Criteria

* Report food allergies or intolerance or health conditions that would prevent consumption of provided and recommended foods.
* Participation in another concurrent nutrition research study.
* If premenopausal (\<55 years of age), they are pregnant or intend to become pregnant during the course of the study, or are not using a birth control method to prevent pregnancy.
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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USDA Human Nutrition Research Center on Aging

FED

Sponsor Role collaborator

Tufts University

OTHER

Sponsor Role lead

Responsible Party

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Susan Roberts

Director and Senior Scientist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Susan B Roberts, PhD

Role: PRINCIPAL_INVESTIGATOR

Tufts University

Locations

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International Partnership for Health Development

Bissau, , Guinea-Bissau

Site Status

Countries

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Guinea-Bissau

Other Identifiers

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12377

Identifier Type: -

Identifier Source: org_study_id

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