Adverse Drug Reactions in Pediatrics: Experience of a Regional Pharmacovigilance Center

NCT ID: NCT03316014

Last Updated: 2017-10-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

632 participants

Study Classification

OBSERVATIONAL

Study Start Date

1985-01-31

Study Completion Date

2014-12-31

Brief Summary

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Aim. - To describe the adverse drug reactions (ADR) and the drugs involved in pediatrics.

Methods. - An observational study on all ADR notifications recorded in the French pharmaco-vigilance database by the Regional Pharmacovigilance Center of Champagne-Ardenne between 1 January 1985 and 31 December 2014 involving children from 0 to 17 years inclusive was performed. For all notifications, we studied the patient and the ADR characteristics

Detailed Description

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Pediatry aged under 18 years accounted for around 22% of the French general population.

Data regarding drug safety from clinical trials are insufficient in this population.

Aim. - To describe the adverse drug reactions (ADR) and the drugs involved in pediatrics.

Methods. - An observational study on all ADR notifications recorded in the French pharmaco-vigilance database by the Regional Pharmacovigilance Center of Champagne-Ardenne between 1 January 1985 and 31 December 2014 involving children from 0 to 17 years inclusive was performed. For all notifications, we studied the patient and the ADR characteristics.

Conditions

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Child With Adverse Drug Reactions

Keywords

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Pediatry; Adverse drug reactions; Pharmacovigilance

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Adverse drug reaction

Children from 0 to 17 years inclusive with ADR notifications recorded in the French pharmaco-vigilance database by the Regional Pharmacovigilance Center of Champagne-Ardenne between 1 January 1985 and 31 December 2014

Adverse drug reaction

Intervention Type OTHER

description of the adverse drug reactions (ADR) and the drugs involved in pediatrics

Interventions

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Adverse drug reaction

description of the adverse drug reactions (ADR) and the drugs involved in pediatrics

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Children from 0 to 17 years inclusive
* Who presented an adverse drug reaction notified to the Regional Pharmacovigilance Center of Champagne-Ardenne

Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CHU de Reims

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

References

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Saint-Martin C, Kanagaratnam L, de Boissieu P, Azzouz B, Abou Taam M, Trenque T. [Adverse drug reactions in pediatrics: Experience of a regional pharmacovigilance center]. Therapie. 2016 Oct;71(5):467-473. doi: 10.1016/j.therap.2016.04.001. Epub 2016 Apr 11. French.

Reference Type BACKGROUND
PMID: 27203165 (View on PubMed)

Other Identifiers

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2016Ao003

Identifier Type: -

Identifier Source: org_study_id