Lymph Node Metastases and Arterial Ligation in Rectal Cancer Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

151 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-31

Study Completion Date

2016-12-31

Brief Summary

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Lymph node status is of major prognostic importance in non-metastatic rectal cancer. For oncological reasons, central arterial ligation of the inferior mesenteric artery (IMA) is suggested. However, there is no conclusive evidence presented for this procedure.

This study aimed at investigating the localisation of lymph node metastases and the role of central versus peripheral arterial ligation of in rectal cancer specimens.

Detailed Description

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Prospective population-based study of specimens from patients that underwent surgical resection for rectal cancer in Västmanland County, Sweden. Specimens were divided in 3 sections (A-C) and the total amount of lymph nodes and the location of lymph node metastases were analysed.

Multivariate analysis was used to explore the relationship between lymph node counts and age, gender, BMI, preoperative oncological treatment, type of surgery, tumour stage, vessel and specimen length.

Conditions

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Lymph Node Metastases

Keywords

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rectal cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* All patients that were curatively operated for rectal cancer in Västmanlands county 2012-2016.

Exclusion Criteria

* Patients that were not operated or had another type of cancer.

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Catarina Tiselius

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Catarina Tiselius, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Region Västmanland

Other Identifiers

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Dnr2013/099

Identifier Type: -

Identifier Source: org_study_id