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Compare the Analgesic Effect of Different Anesthesia and Postoperative Analgesic Methods in Uniportal VATS Lung Surgery

NCT ID: NCT03311737

Last Updated: 2017-10-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-19

Study Completion Date

2018-03-31

Brief Summary

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This is a single center, randomized, single blind study to compare the analgesic effect of different anesthesia and postoperative analgesic methods in uniportal VATS lung surgery.

Detailed Description

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Combining epidural with general anesthesia is regarded as the gold standard of general thoracic surgery. The uniportal VATS lung surgery have advantages of minimal invasive surgical incision, less postoperative pain, and so on. Whether general anesthesia can become an alternative method of combining epidural with general anesthesia in uniportal VATS lung surgery, investigators thus plan to make a comparison on intraoperative stress response, postoperative pain, immune function of patients，and hospital expenses.

Conditions

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Postoperative Pain Single-incision Thoracoscopic Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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general anesthesia group

The patients in this group receive general anesthesia preoperatively, and use patient controlled intravenous analgesia postoperatively.

Group Type EXPERIMENTAL

general anesthesia

Intervention Type COMBINATION_PRODUCT

The investigators used general anesthesia preoperatively in uniportal VATS lung surgery

epidural group

The patients in this group receive general anesthesia combined with epidural anesthesia, and use patient controlled epidural analgesia postoperatively.

Group Type ACTIVE_COMPARATOR

epidural anesthesia

Intervention Type COMBINATION_PRODUCT

The investigators used general anesthesia combined with epidural anesthesia preoperatively in uniportal VATS lung surgery

Interventions

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general anesthesia

The investigators used general anesthesia preoperatively in uniportal VATS lung surgery

Intervention Type COMBINATION_PRODUCT

epidural anesthesia

The investigators used general anesthesia combined with epidural anesthesia preoperatively in uniportal VATS lung surgery

Intervention Type COMBINATION_PRODUCT

Eligibility Criteria

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Inclusion Criteria

* Patients elective uniportal VATS lung surgery;
* BMI 18-30 kg/m2.

Exclusion Criteria

* Patient refuse;
* ASA≥3;
* Patients allergic to use anesthetics (propofol,rocuronium), patients with liver and/or kidney and/or mental dysfunction.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Zhongshan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Zhongshan Hospital

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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yi li, Ph.D

Role: CONTACT

Phone: 13816836628

Email: [email protected]

xiangting li, B.S.

Role: CONTACT

Phone: 13671864990

Email: [email protected]

Facility Contacts

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yi li, Ph.D

Role: primary

xiangting li, B.S.

Role: backup

Other Identifiers

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zs20170511

Identifier Type: -

Identifier Source: org_study_id