Immunological Profile of Solid Tumors Sample

NCT ID: NCT03311100

Last Updated: 2018-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1040 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-04-06

Study Completion Date

2020-04-06

Brief Summary

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It has become clear in the recent year that the nature of the immune cells infiltrate within a tumor was essential in the control of the tumor growth. This so-called immune contexture does vary between cancer types and in response to treatments. In this context, this trial is a non-interventional, mono-centric in patients with solid tumors. Samples in paraffin-embedded material block of biopsies or surgical pieces (either primitive tumor or metastases) will be analysed. For each sample, clinically relevant data associated with treated cancer and needed for characterization of tumor microenvironment will be documented.

This trial is, through accessing to well documented selected archival tumor materials, to validate selected biomarker for early phase trial.

Detailed Description

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Conditions

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Solid Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Lung cancer

immunohistochemistry assay

Intervention Type OTHER

biomarkers expression

Central Nervous System Cancers

immunohistochemistry assay

Intervention Type OTHER

biomarkers expression

Head and Neck and upper aero-digestive tract cancers

immunohistochemistry assay

Intervention Type OTHER

biomarkers expression

Skin cancers

immunohistochemistry assay

Intervention Type OTHER

biomarkers expression

Sarcomas

immunohistochemistry assay

Intervention Type OTHER

biomarkers expression

Urothelial cancer

immunohistochemistry assay

Intervention Type OTHER

biomarkers expression

Hepatocarcinoma

immunohistochemistry assay

Intervention Type OTHER

biomarkers expression

Interventions

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immunohistochemistry assay

biomarkers expression

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Sample must have had a valid written informed consent for available archival tumor samples for scientific purposes.
* Sample from patients with histologically documented cancer in target population.

Exclusion Criteria

* Samples from subject unwilling to give their informed consent;
* Unusable sample or biologically deteriorated.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Innate Pharma

INDUSTRY

Sponsor Role collaborator

Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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ARNAUD Jean-Olivier, Director

Role: STUDY_DIRECTOR

Assistance Publique Hôpitaux de Marseille

Locations

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Assistance Publique Hôpitaux de Marseille

Marseille, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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BARLESI Fabrice, PU-PH

Role: CONTACT

491385590 ext. +33

Facility Contacts

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Fabrice BARLESI, PU-PH

Role: primary

491385590 ext. +33

Other Identifiers

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2017-A00778-45

Identifier Type: REGISTRY

Identifier Source: secondary_id

2016-53

Identifier Type: -

Identifier Source: org_study_id

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