The Role of Biodentine in Class V Dental Lesions on Oral Health Related Quality of Life

NCT ID: NCT03304184

Last Updated: 2021-07-19

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE3

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-28

Study Completion Date

2019-10-09

Brief Summary

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The study will compare two different dental materials on dental lesions near the gum line that cause chronic pain on oral health related quality of life.

Detailed Description

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The study will compare two different dental materials on dental lesions near the gum line. One of the materials is tooth colored and the other material is white but both materials use different mechanisms to attach to the teeth and may have different outcomes. The study will determine if one material is more effective in relieving chronic pain. In addition, we will evaluate changes in oral health related quality of life after the placement of the two different dental materials.

Conditions

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Quality of Life Cervical Abrasion

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

One group will be treated with a tooth colored filling that will be placed near the gum line. The second group will be treated with a white colored filling that will be placed near the gum line.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Photac-fil

Participants will have a restoration placed with photac-fil in the lesion near the gum line.

Group Type PLACEBO_COMPARATOR

Photac-fil

Intervention Type DEVICE

Application of a tooth colored filling in a non-cavitated dental lesion.

Biodentine

Participants will have a restoration placed with Biodentine in the lesion near the gum line.

Group Type EXPERIMENTAL

Biodentine

Intervention Type DEVICE

Application of a white colored filling in a non-cavitated dental lesion.

Interventions

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Photac-fil

Application of a tooth colored filling in a non-cavitated dental lesion.

Intervention Type DEVICE

Biodentine

Application of a white colored filling in a non-cavitated dental lesion.

Intervention Type DEVICE

Other Intervention Names

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Resin modified glass ionomer

Eligibility Criteria

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Inclusion Criteria

* Males and females age 18-64
* Chief complaint associated with pain from cold or hot
* Chronic sensitivity associated with supragingival lesions
* Pain not associated with decay
* Fluent in English and able to read English at a 6th grade level
* Pulpal response \<40 via pulp tester
* Active salivary flow from palpation of parotid and submandibular glands
* Patients self reporting pain over 6/10 in the past week and/or the past 2 months

Exclusion Criteria

* Pregnant women
* Patients taking benzodiazepines, narcotics and multiple antidepressants for pain management not associated with the oral cavity
* Unexplained dry mouth
* Patients taking two or more medications associated with dry mouth
* Pulpal response \>40 via pulp tester
* Patients requiring treatment for more than 5 decayed sites, periodontal disease and root canal therapy
* Complicated medical history (\>4 concurrent treatment for systemic diseases)
* Lesion \>1mm below the gum line
Minimum Eligible Age

18 Years

Maximum Eligible Age

64 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Michigan

OTHER

Sponsor Role lead

Responsible Party

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Elizabeth Van Tubergen

Clinical Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Dental School

Ann Arbor, Michigan, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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HUM00111890

Identifier Type: -

Identifier Source: org_study_id

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