Preoperative Oral Pregabalin Effect on Inhalational Anesthetic Requirements ln Hysterectomy Under General Anesthesia
NCT ID: NCT03302208
Last Updated: 2018-01-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
50 participants
INTERVENTIONAL
2017-06-29
2017-09-20
Brief Summary
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Detailed Description
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The investigators aim to compare the efficacy of preoperative oral pregabalin versus placebo in reducing intraoperative isoflurane requirements needed to maintain intraoperative hemodynamic stability (Blood pressure and heart rate within ± 20% of baseline measurements) in female patients ASA I/II undergoing elective abdominal hysterectomy surgery under general anaesthesia.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
HEALTH_SERVICES_RESEARCH
DOUBLE
Study Groups
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pregabalin group
Pregabalin
Pregabalin capsule 150 mg oral
placebo group
Placebo
Placebo
Interventions
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Pregabalin
Pregabalin capsule 150 mg oral
Placebo
Placebo
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* American Society of Anaesthesiology (ASA) physical status I or II.
Exclusion Criteria
* Allergy or hypersensitivity to pregabalin.
* Patient on calcium channel blocker or anticonvulsant.
18 Years
60 Years
FEMALE
No
Sponsors
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Nesrine El-Refai
OTHER
Responsible Party
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Nesrine El-Refai
professor
Locations
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Cairo University
Cairo, Zamalek, Egypt
Countries
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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UTF-9
Identifier Type: -
Identifier Source: org_study_id
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