Diagnostic and Therapeutic Approaches to Hyperinflation and Small Airway Disease in COPD
NCT ID: NCT03287921
Last Updated: 2020-03-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
26 participants
OBSERVATIONAL
2017-10-02
2019-04-11
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CROSSOVER
PROSPECTIVE
Study Groups
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mono bronchodilatation
patients with COPD and features of hyperinflation and small airway disease
mono bronchodilatation
within indication according to current GOLD recommendation
dual bronchodilatation
within indication according to current GOLD recommendation
dual bronchodilatation
patients with COPD and features of hyperinflation and small airway disease
mono bronchodilatation
within indication according to current GOLD recommendation
dual bronchodilatation
within indication according to current GOLD recommendation
Interventions
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mono bronchodilatation
within indication according to current GOLD recommendation
dual bronchodilatation
within indication according to current GOLD recommendation
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* lung function testing consistent with hyperinflation or peripheral obstruction
* emphysema in imaging
* symptoms (dyspnea, cough, sputum) and risk factors (\>= 10 pack years)
* indication for bronchodilator therapy
Exclusion Criteria
* indication for dual bronchodilator therapy, triple therapy or inhaled steroid
* contraindication for cardiopulmonary exercise testing
* unwilling to participate
18 Years
ALL
No
Sponsors
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Universitätsmedizin Mannheim
OTHER
Responsible Party
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Dr. Frederik Trinkmann
Principal Investigator
Principal Investigators
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Frederik Trinkmann, MD
Role: PRINCIPAL_INVESTIGATOR
University Medical Center Mannheim
Locations
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University Medical Center Mannheim
Mannheim, , Germany
Countries
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Other Identifiers
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MBW-hyperinflation
Identifier Type: -
Identifier Source: org_study_id
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