Association Between Dietary Habits and Gestational Diabetes

NCT ID: NCT03287297

Last Updated: 2017-09-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-12-01

Study Completion Date

2019-12-01

Brief Summary

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Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance of varying severity with onset or first recognition during pregnancy. The diagnosis of gestational diabetes is important, because of the increased risk of adverse maternal and feto-neonatal outcomes. In addition, GDM also confers a future risk of type 2 diabetes to mothers and their fetus. Dietary components associated with GDM risk include macronutrients, micronutrients, and individual foods, such as refined carbohydrates, saturated fats, soft drinks and processed meats. The Pre-pregnancy dietary patterns may affect women risk of developing GDM. A diet high in red and processed meat was associated with a significantly elevated risk.

Detailed Description

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\*Aim of the work: To investigate associations between maternal dietary patterns and GDM.

* Patients and Methods:

* Study design: A cross sectional study was conducted.
* Study site: GDM Outpatient Clinic of Assiut University Hospital.
* Study population: The study will include all pregnant women at 24th to 28th gestational age, who attending to GDM Outpatient Clinic during the period of The Study.
* Inclusion criteria include pregnant women at 24th to 28th age of gestation.
* Exclusion criteria include pre-gestational diabetic women and pregnant women before and after 24th -28th week of gestation.
* Instrument: Structured designed questionnaire: Which consists of socio-demographic characteristics, Medical and obstetric history and other risk factors for GDM including previous GDM, family history of diabetes, twins in current pregnancy, history of PCO and macrosomic baby in current or previous pregnancy, also contains information about regularity and frequencies of daily meals taken by the women, and information about food group frequencies per week, food groups like vegetables, fruits, fast food , red and processed meat, fish and seafood, whole grains, cereal fiber, sweetened beverage, dessert food and use of multivitamins.
* Data collection: Direct interview will be done with each participant separately for filling the food frequency questionnaire by the researcher himself during the period from January 2017 to June 2017
* Clinical examination:

* BP (mmHg)
* Pulse
* Body Weight (kg)
* Height (cm)
* BMI

Laboratory Examination

* OGTT (75gm) 2hr
* HBA1c (if Bl. Glucose ≥ 200mg/dl).

Conditions

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Gestational Diabetes Mellitus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

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OGTT & HBA1c

oral glucose tolerance test \& HBA1c: by measuring glycated hemoglobin

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* include pregnant women at 24th to 28th age of gestation.

Exclusion Criteria

* include pre-gestational diabetic women and pregnant women before and after 24th -28th week of gestation.
Minimum Eligible Age

21 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Mahmoud Mokhtar Abdel-Hameed

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Nabila Fayek, Professor

Role: CONTACT

0201226341736

Naglaa Mohamed, Lecturer

Role: CONTACT

0201004069708

References

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Alfadhli EM. Gestational diabetes mellitus. Saudi Med J. 2015 Apr;36(4):399-406. doi: 10.15537/smj.2015.4.10307.

Reference Type BACKGROUND
PMID: 25828275 (View on PubMed)

Bhatt AA, Dhore PB, Purandare VB, Sayyad MG, Mandal MK, Unnikrishnan AG. Gestational diabetes mellitus in rural population of Western India - Results of a community survey. Indian J Endocrinol Metab. 2015 Jul-Aug;19(4):507-10. doi: 10.4103/2230-8210.159061.

Reference Type BACKGROUND
PMID: 26180767 (View on PubMed)

Kampmann U, Madsen LR, Skajaa GO, Iversen DS, Moeller N, Ovesen P. Gestational diabetes: A clinical update. World J Diabetes. 2015 Jul 25;6(8):1065-72. doi: 10.4239/wjd.v6.i8.1065.

Reference Type BACKGROUND
PMID: 26240703 (View on PubMed)

Poomalar GK, Rangaswamy V. A comparison of fasting plasma glucose and glucose challenge test for screening of gestational diabetes mellitus. J Obstet Gynaecol. 2013 Jul;33(5):447-50. doi: 10.3109/01443615.2013.771156.

Reference Type BACKGROUND
PMID: 23815193 (View on PubMed)

Agarwal MM. Gestational diabetes mellitus: An update on the current international diagnostic criteria. World J Diabetes. 2015 Jun 25;6(6):782-91. doi: 10.4239/wjd.v6.i6.782.

Reference Type BACKGROUND
PMID: 26131321 (View on PubMed)

Ovesen PG, Jensen DM, Damm P, Rasmussen S, Kesmodel US. Maternal and neonatal outcomes in pregnancies complicated by gestational diabetes. a nation-wide study. J Matern Fetal Neonatal Med. 2015;28(14):1720-4. doi: 10.3109/14767058.2014.966677. Epub 2015 Jan 8.

Reference Type BACKGROUND
PMID: 25228278 (View on PubMed)

Seshiah V; Diabetes in Pregnancy Study Group. Fifth National Conference of Diabetes in Pregnancy Study Group, India. J Assoc Physicians India. 2010 May;58:329-30. No abstract available.

Reference Type BACKGROUND
PMID: 21117358 (View on PubMed)

Zhang C, Ning Y. Effect of dietary and lifestyle factors on the risk of gestational diabetes: review of epidemiologic evidence. Am J Clin Nutr. 2011 Dec;94(6 Suppl):1975S-1979S. doi: 10.3945/ajcn.110.001032. Epub 2011 May 25.

Reference Type BACKGROUND
PMID: 21613563 (View on PubMed)

Zhang C, Schulze MB, Solomon CG, Hu FB. A prospective study of dietary patterns, meat intake and the risk of gestational diabetes mellitus. Diabetologia. 2006 Nov;49(11):2604-13. doi: 10.1007/s00125-006-0422-1. Epub 2006 Sep 7.

Reference Type BACKGROUND
PMID: 16957814 (View on PubMed)

Qiu C, Zhang C, Gelaye B, Enquobahrie DA, Frederick IO, Williams MA. Gestational diabetes mellitus in relation to maternal dietary heme iron and nonheme iron intake. Diabetes Care. 2011 Jul;34(7):1564-9. doi: 10.2337/dc11-0135.

Reference Type BACKGROUND
PMID: 21709295 (View on PubMed)

Other Identifiers

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17100275

Identifier Type: -

Identifier Source: org_study_id