Observational Registry Characterizing the CTAG Device With ACTIVE CONTROL

NCT ID: NCT03286400

Last Updated: 2020-12-17

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

127 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-10-18

Study Completion Date

2019-10-09

Brief Summary

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Collect real-world clinical and device-specific outcomes of the GORE® TAG® Conformable Thoracic Stent Graft featuring ACTIVE CONTROL System (CTAG Device with ACTIVE CONTROL) in the treatment of aortic disease as part of routine clinical practice.

Detailed Description

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This is an observational, prospective, single-arm, post-market registry designed to collect real-world clinical and device specific outcomes of the GORE® TAG® Conformable Thoracic Stent Graft featuring ACTIVE CONTROL System (CTAG Device with ACTIVE CONTROL) in the treatment of aortic disease as part of routine clinical practice. A maximum of 20 clinical investigative sites in Europe will participate and up to 125 patients will be enrolled in this registry. All consecutive patients meeting protocol selection criteria, consented, with an intention to be treated with the CTAG Device with ACTIVE CONTROL will be included and followed through one year per institutional standard of care.

Conditions

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Thoracic Diseases

Keywords

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CTAG TEVAR

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CTAG Device with ACTIVE CONTROL

All consecutive patients meeting protocol selection criteria, consented, with an intention to be treated with CTAG Device with ACTIVE CONTROL.

CTAG Device with ACTIVE CONTROL

Intervention Type DEVICE

Intent to treat with the CTAG Device with ACTIVE CONTROL in the treatment of aortic diseases as part of routine clinical practice.

Interventions

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CTAG Device with ACTIVE CONTROL

Intent to treat with the CTAG Device with ACTIVE CONTROL in the treatment of aortic diseases as part of routine clinical practice.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Age ≥ 18 years
2. Signed informed consent form
3. Willingness, in the opinion of the investigator, to adhere to standard of care follow-up requirements
4. Surgical indication for TEVAR based on investigator's best medical judgment
5. Intent to treat with CTAG Device with ACTIVE CONTROL.

Exclusion Criteria

1. Paraplegia or paraparesis at initial presentation
2. Participation in concurrent research study or registry which may confound registry results, unless approved by Sponsor
3. Prior implantation of a thoracic stent graft
4. Pregnant or breast-feeding female at time of informed consent signature
5. Life expectancy \< 1 year due to comorbidities
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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W.L.Gore & Associates

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Giovanni Torsello, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

St Franziskus Hospital GmbH

Locations

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University Hospital Angers

Angers, , France

Site Status

CHU Strasbourg

Strasbourg, , France

Site Status

University Hospital Köln

Cologne, , Germany

Site Status

University of Heidelberg

Heidelberg, , Germany

Site Status

St. Franziskus Hospital GmbH

Münster, , Germany

Site Status

University Hospital Regensburg

Regensburg, , Germany

Site Status

Hospital Civili Brescia

Brescia, , Italy

Site Status

Ospedali dei Colli - Monaldi

Napoli, , Italy

Site Status

Azienda Ospedaliers San Camilla Forlanni

Roma, , Italy

Site Status

University Hospital Amsterdam

Amsterdam, , Netherlands

Site Status

St Antonius Hospital

Nieuwegein, , Netherlands

Site Status

Erasmus Medical Center

Rotterdam, , Netherlands

Site Status

Hospital Universitario Central de Asturias

Oviedo, , Spain

Site Status

Hospital Clínico Santiago de Compostela

Santiago de Compostela, , Spain

Site Status

Hospital Universitario Miguel Servet

Zaragoza, , Spain

Site Status

Orebro University Hospital

Örebro, , Sweden

Site Status

Uppsala University

Uppsala, , Sweden

Site Status

Leeds General Infirmary

Leeds, , United Kingdom

Site Status

St George's Vascular Institute

London, , United Kingdom

Site Status

St Thomas' London / Guy's Hospital

London, , United Kingdom

Site Status

Countries

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France Germany Italy Netherlands Spain Sweden United Kingdom

References

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Torsello GF, Argyriou A, Stavroulakis K, Bosiers MJ, Austermann M, Torsello GB; SURPASS Registry Collaborators. One-Year Results From the SURPASS Observational Registry of the CTAG Stent-Graft With the Active Control System. J Endovasc Ther. 2020 Jun;27(3):421-427. doi: 10.1177/1526602820913007. Epub 2020 Mar 20.

Reference Type DERIVED
PMID: 32193990 (View on PubMed)

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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TAG 15-03

Identifier Type: -

Identifier Source: org_study_id