Comprehensive Acupuncture for Depressive Disorder With Comorbid Psychogenic Pain
NCT ID: NCT03282110
Last Updated: 2017-11-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
EARLY_PHASE1
60 participants
INTERVENTIONAL
2017-11-30
2019-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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ta-VNS & Electro-acupuncture
1. Device:ta-VNS(transcutaneous vagus nerve stimulation):2 times per day,5 consecutive days per week for two months
2. Other:Electro-acupuncture:3 times per week, once every other day for two months
ta-VNS
The transcutaneous vagus nerve stimulation (taVNS) at auricular concha is a typical representative of TCM modernization. The taVNS regulates the autonomic nervous system, which shows a good therapeutic effect for the treatment of depression.
Electro-acupuncture
one of the most common acupuncture methods, selecting acupoints based on traditional Chinese medicine theory. It exerts the function to regulate qi and blood circulation and balance Yang and Yin energy inside body.
Citalopram
citalopram for oral administration; 10mg for the first 1-3 days, 20mg for the following 4-7 days；40mg for the left days within two months
Citalopram
Citalopram is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class.It has U.S. Food and Drug Administration approval to treat major depression.
Interventions
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ta-VNS
The transcutaneous vagus nerve stimulation (taVNS) at auricular concha is a typical representative of TCM modernization. The taVNS regulates the autonomic nervous system, which shows a good therapeutic effect for the treatment of depression.
Electro-acupuncture
one of the most common acupuncture methods, selecting acupoints based on traditional Chinese medicine theory. It exerts the function to regulate qi and blood circulation and balance Yang and Yin energy inside body.
Citalopram
Citalopram is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class.It has U.S. Food and Drug Administration approval to treat major depression.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Age from 18 to 50 year-old
* Patients with the first onset depression
* Patients with mild-to-moderate depression scored 12-30 by Montgomery scale
* Patients with one psychogenic pain at least, and the degree of VAS is 3 or more
* Volunteer participants willing to cooperate and obeying the treatment
Exclusion Criteria
* Patients with severe primary diseases and acute diseases of heart, brain, liver, kidney and hematopoietic systems and infectious disease, malignant tumor
* Patients who can't stop taking drugs according to the requirement in the treatment period
* Patients with a history of schizophrenia and other mental disorders
* Patients with cognitive impairment or personality disorders
* Patients have serious suicide idea or suicidal behavior
18 Years
50 Years
ALL
No
Sponsors
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China Academy of Chinese Medical Sciences
OTHER
Responsible Party
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Peijing Rong
The deputy director of Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences
Principal Investigators
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Peijing Rong, Dotor
Role: STUDY_DIRECTOR
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences
Zhangjing Zhang, Dotor
Role: STUDY_DIRECTOR
The School of Chinese Medicine, The University of Hong Kong
Central Contacts
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Other Identifiers
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ChinaACMS-3
Identifier Type: -
Identifier Source: org_study_id