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Anastomotic Leakage After Anterior Resection of Rectal Cancer

NCT ID: NCT03281070

Last Updated: 2017-12-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-10-01

Study Completion Date

2018-05-01

Brief Summary

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Anastomotic leakage (AL) is one of the most-feared postoperative complications after anterior resection of rectal cancer. This complication compromises both short term and long term outcome of patients. The incidence of AL after anterior resection was approximately 6-11%. Although several risk factors for AL such as male sex, smoking, tumor location, longer operative time, intraoperative blood loss had been reported in previous studies, the incidence of AL did not meet a significant decrease. So far there is no multi-site observational study on incidence and risk factors of AL after anterior resection in China, therefore this study aims to work on this issue and provide evidence for clinical practice.

Detailed Description

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Conditions

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Rectal Cancer

Keywords

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Anastomotic leakage Anterior resection Risk factors Incidence Rectal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* adenocarcinoma of the rectum by biopsy
* single lesion
* anterior resection was performed
* anastomosis using circular stapler

Exclusion Criteria

* history of colorectal cancer surgery
* emergency surgery because of bowel obstruction, bleeding or perforation
* colo-anal anastomosis
* subtotal colectomy
* total colectomy
* abdominal perineal resection
* Hartmann procedure
* pull out anastomosis
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beijing Friendship Hospital

OTHER

Sponsor Role lead

Responsible Party

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Zhongtao Zhang

Department of General Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Beijing Friendship Hospital

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Hongwei Yao, M.D.

Role: CONTACT

Phone: +8613611015609

Email: [email protected]

Jun Li, M.D.

Role: CONTACT

Phone: +8613811379656

Email: [email protected]

Facility Contacts

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Hongwei Yao, M.D.

Role: primary

Other Identifiers

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CR-AL

Identifier Type: -

Identifier Source: org_study_id