Improving Cardiac Secondary Prevention

NCT ID: NCT03269708

Last Updated: 2024-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-03-01

Study Completion Date

2024-09-30

Brief Summary

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The purpose of this study is to determine whether providing individuals with personalized information on cellular aging, including telomere length, will stimulate them to adhere to cardiac prevention strategies and improve exercise capacity.

Detailed Description

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Individuals who have sustained a heart attack are at considerable risk for future cardiac events. A cardiac rehabilitation and exercise program can reduce this risk but it remains a challenge to adopt optimum lifestyle changes. We will determine whether providing individuals with information on leukocyte telomere length, will motivate them to improve their exercise performance. We will test whether professionally conveying this information will stimulate an individual to adhere to proven cardiac prevention strategies, looking at the extent to which one's exercise capacity improves over time.

Conditions

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Myocardial Infarction Secondary Prevention

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Control

Participants receive standard care in cardiac rehabilitation program

Group Type NO_INTERVENTION

No interventions assigned to this group

Knowledge transfer group

Participants receive standard care in cardiac rehabilitation program plus education regarding telomere length

Group Type EXPERIMENTAL

Education regarding telomere length

Intervention Type BEHAVIORAL

Teaching concepts of cellular aging and telomere length

Interventions

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Education regarding telomere length

Teaching concepts of cellular aging and telomere length

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1\. Individuals who have sustained a myocardial infarction and entered the cardiac rehabilitation program

Exclusion Criteria

1. Individuals with genetic mutations that affect telomere length
2. Individuals who may not have the mental capacity to understanding the ramifications of risk biomarkers
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Western University, Canada

OTHER

Sponsor Role lead

Responsible Party

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Geoffrey Pickering MD PhD

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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J. Geoffrey Pickering, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Western Faculty

Locations

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London Health Sciences Centre, Western University

London, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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109209

Identifier Type: -

Identifier Source: org_study_id

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