PTM202 for the Treatment of Environmental Enteric Dysfunction (EED)

NCT ID: NCT03263871

Last Updated: 2019-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-14

Study Completion Date

2019-02-15

Brief Summary

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The purpose of this study is to assess the effectiveness of PTM202 in treating environmental enteric dysfunction.

Detailed Description

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Conditions

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Environmental Enteric Dysfunction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Caregivers Outcome Assessors

Study Groups

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Intervention

PTM202 and micro-nutrient sprinkles

Group Type EXPERIMENTAL

PTM202

Intervention Type DIETARY_SUPPLEMENT

PTM202 given twice daily for 30 days.

micro-nutrient sprinkles

Intervention Type DIETARY_SUPPLEMENT

Micro-nutrient sprinkles will be given twice daily for 30 days.

Control

micro-nutrient sprinkles

Group Type OTHER

micro-nutrient sprinkles

Intervention Type DIETARY_SUPPLEMENT

Micro-nutrient sprinkles will be given twice daily for 30 days.

Interventions

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PTM202

PTM202 given twice daily for 30 days.

Intervention Type DIETARY_SUPPLEMENT

micro-nutrient sprinkles

Micro-nutrient sprinkles will be given twice daily for 30 days.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Aged 6 - 9 months old
* -1\> Weight-for-age Z score \> -3
* Parental consent to participate and receive daily supplementation with either PTM202 and/or micro-nutrient sprinkles, participate in specimen collection

Exclusion Criteria

* Presence of known kidney, liver, heart, developmental, or neurologic disease
* Allergy to milk and/or egg (assessed by history)
* Milk intolerance (assessed by history)
* Abnormal liver or kidney function tests
* Family is planning to move from the study area or children is enrolled to the other clinical trial within 3 months of follow up
* Child being exclusively breast fed at the time of enrollment
Minimum Eligible Age

6 Months

Maximum Eligible Age

9 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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International Centre for Diarrhoeal Disease Research, Bangladesh

OTHER

Sponsor Role collaborator

Virginia Commonwealth University

OTHER

Sponsor Role collaborator

University of Virginia

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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International Centre for Diarrhoeal Disease Research, Bangladesh

Dhaka, , Bangladesh

Site Status

Countries

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Bangladesh

Other Identifiers

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19993

Identifier Type: -

Identifier Source: org_study_id

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