Gammaglobulins Level is Predictive Factor of Evolution in Sarcoidosis

NCT ID: NCT03259282

Last Updated: 2018-04-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

78 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-03-07

Study Completion Date

2017-03-22

Brief Summary

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Evaluation of the rate of achievement of serum protein electrophoresis (PPE) in diagnosis in a retrospective cohort of patients at Rennes University Hospital

Detailed Description

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In 50% of cases, sarcoidosis is associated with polyclonal hypergammaglobulinemia. The other forms have a normal gamma globulin level.

The level of gamma globulinemia has not yet been studied as an evolutionary predictive factor. Furthermore, there are disseminated granulomatoses sharing common characteristics with sarcoidosis, associated with Common Variable Immunodeficiency deficit (DICV) type Primary Immunodeficiency syndrome (DIP), thus occurring in hypogammaglobulinemic patients.

Conditions

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Sarcoidosis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Interventions

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Analysis of gamma globulin

Electrophoresis of proteins

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

\- Patients newly diagnosed with sarcoidosis

Exclusion Criteria

* Comorbidity responsible for a change in the level of gamma globulin
* Other etiology of granulomatosis
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rennes University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU de Rennes

Rennes, , France

Site Status

Countries

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France

Other Identifiers

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35RC16_3046_GAMES

Identifier Type: -

Identifier Source: org_study_id

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