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Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)

NCT ID: NCT03246269

Last Updated: 2018-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

334 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-12-31

Study Completion Date

2017-04-30

Brief Summary

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This observational cohort study in healthy volunteers establishes normative data for the German version of the Montreal Cognitive Assessment (MoCA) and investigates the possible impacts of demographics on the MoCA total score.

Detailed Description

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The Montreal Cognitive Assessment (MoCA) is a short tool to evaluate a multitude of cognitive domains (visuospatial / executive functioning, object naming, memory, attention, language, abstraction, orientation). The original English MoCA consistently showed very high sensitivity and specificity in distinguishing patients with mild cognitive impairment from healthy controls. Therefore it is an excellent tool for early recognition of cognitive disorders. Based on a Canadian sample, the MoCA proposes a cut-off-value of 26/30 points. However, there is increasing evidence of intercultural differences in terms of the best cut-off-score. In addition the original version only slightly corrects for possible influences of education - an adjustment for age- or gender-related effects is missing. Therefore, the aim of our study was to investigate the possible impacts of demographics on the MoCA total score and to provide normative values for a German-speaking population.

Conditions

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Cognitive Impairment Cognitive Decline Cognition Disorders Cognitive Symptom Cognitive Change Cognitive Deterioration Cognitive Abnormality Cognitive Impairment, Mild Cognition Disorders in Old Age Dementia Dementia Alzheimers Dementia, Alzheimer Type Dementia, Mild Dementia of Alzheimer Type

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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MoCA cohort

The German MoCA is administered once to all study participants.

MoCA

Intervention Type DIAGNOSTIC_TEST

Interventions

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MoCA

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age ≥65 years
* Education ≥7 years
* Fluency in the German language
* Written informed consent

Exclusion Criteria

* History of cognitive impairment
* Depression
* Severe sensory or motor impairment interfering with cognitive testing
* Serious somatic disease
* Disease or event affecting the central nervous system
* Cerebrovascular disease
* Regular medication with psychoactive drugs except for benzodiazepines
* Participation in a cognitive study within the last 3 months
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Andreas Monsch

OTHER

Sponsor Role lead

Responsible Party

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Andreas Monsch

PhD

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Alessandra Thomann, MSc

Role: PRINCIPAL_INVESTIGATOR

Felix Platter Hospital Basel

Nicolai Goettel, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Basel, Switzerland

Raphael Monsch, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Basel, Switzerland

Manfred Berres, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Applied Sciences Koblenz

Andreas Monsch, PhD

Role: STUDY_CHAIR

Felix Platter Hospital Basel

Other Identifiers

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MoCA-Norm

Identifier Type: -

Identifier Source: org_study_id