Ultrasound-guided Block for Thoracic Surgery Pain

NCT ID: NCT03240562

Last Updated: 2018-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

89 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-08-03

Study Completion Date

2017-12-30

Brief Summary

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The investigators aimed to assess Ultrasounde- guided serratus anterior plane block can be effective in acute postoperative pain following thoracic surgery.

Detailed Description

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Analgesic options for thoracotomy are various with each having their own merits and demerits.Thoracic epidural is said to be the gold standard for management of thoracotomy pain. However, it is invasive procedure and many side effects. Other options include paravertebral block, interpleural block, intrathecal opioids. Especially, paravertebral block is thought good alternative to epidural anethesia. Most of these invasive neuraxial techniques demand normal coagulation parameters to be present.

The serratus anterior plane block(SAPB) was done under ultrasound guidance in the mid-axillary line at the level of the fourth rib and the catheter was placed superficial to the serratus plane. The patient expressed relief in pain within 10 minutes of being given the bolus of local anaesthetic.Pain following thoracotomy is chiefly due to rib retraction, and damage to the serratus/intercostal muscles and intercostal nerves. A SAPB addresses both these aspects. SAPB has been mentioned in previous studies for management of rib fractures and breast surgeries. The investigators try to evaluate whether the SAPB is easy to perform and provides effective analgesia in patients undergoing thoracotomy with minimal side effects.

Conditions

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Postoperative Pain Thoracic Cancer

Keywords

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serratus anterior plane block ultrasound-guided regional anesthesia thoracic surgery postoperative pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Caregivers Outcome Assessors

Study Groups

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IV-PCA group

no block performing, only use intravenous patient controled analgesia(IV-PCA)

Group Type SHAM_COMPARATOR

patient controlled analgesia

Intervention Type DRUG

two groups have same intravenous patient controlled analgesia

SAPB group

serratus anterior plane block(SAPB) and intravenous patient controled analgesia(IV-PCA)

Group Type EXPERIMENTAL

serratus anterior plane block

Intervention Type PROCEDURE

before surgery :ultrasound-guided serratus anterior plane block

patient controlled analgesia

Intervention Type DRUG

two groups have same intravenous patient controlled analgesia

Interventions

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serratus anterior plane block

before surgery :ultrasound-guided serratus anterior plane block

Intervention Type PROCEDURE

patient controlled analgesia

two groups have same intravenous patient controlled analgesia

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

•undergoing thoracic surgery (lobectomy or segmentectomy)

Exclusion Criteria

• allergy to any drugs chronic pain disease with medication psychologic disorder anti-depressant drug chronic kidney disease ( Cr over 2.0 mg/dl) coagulopathy
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Samsung medical center

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Chu GM, Jarvis GC. Serratus Anterior Plane Block to Address Postthoracotomy and Chest Tube-Related Pain: A Report on 3 Cases. A A Case Rep. 2017 Jun 15;8(12):322-325. doi: 10.1213/XAA.0000000000000502.

Reference Type BACKGROUND
PMID: 28614112 (View on PubMed)

Duceau B, Baubillier M, Bouroche G, Albi-Feldzer A, Jayr C. Pupillary Reflex for Evaluation of Thoracic Paravertebral Block: A Prospective Observational Feasibility Study. Anesth Analg. 2017 Oct;125(4):1342-1347. doi: 10.1213/ANE.0000000000002003.

Reference Type BACKGROUND
PMID: 28489642 (View on PubMed)

Liu F, Zhang H, Zuo Y. Bilateral thoracic Paravertebral block for immediate postoperative pain relief in the PACU: a prospective, observational study. BMC Anesthesiol. 2017 Jul 5;17(1):89. doi: 10.1186/s12871-017-0378-3.

Reference Type BACKGROUND
PMID: 28679359 (View on PubMed)

Terkawi AS, Tsang S, Sessler DI, Terkawi RS, Nunemaker MS, Durieux ME, Shilling A. Improving Analgesic Efficacy and Safety of Thoracic Paravertebral Block for Breast Surgery: A Mixed-Effects Meta-Analysis. Pain Physician. 2015 Sep-Oct;18(5):E757-80.

Reference Type BACKGROUND
PMID: 26431130 (View on PubMed)

Wildgaard K, Petersen RH, Hansen HJ, Moller-Sorensen H, Ringsted TK, Kehlet H. Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter. Eur J Cardiothorac Surg. 2012 May;41(5):1072-7. doi: 10.1093/ejcts/ezr151. Epub 2011 Dec 21.

Reference Type BACKGROUND
PMID: 22219442 (View on PubMed)

Madabushi R, Tewari S, Gautam SK, Agarwal A, Agarwal A. Serratus anterior plane block: a new analgesic technique for post-thoracotomy pain. Pain Physician. 2015 May-Jun;18(3):E421-4.

Reference Type BACKGROUND
PMID: 26000690 (View on PubMed)

Other Identifiers

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SMC2017-06-123

Identifier Type: -

Identifier Source: org_study_id