Trial Outcomes & Findings for (-)- Epicatechin Becker Muscular Dystrophy (NCT NCT03236662)

NCT ID: NCT03236662

Last Updated: 2021-11-24

Results Overview

blood biomarker concentration

Recruitment status

COMPLETED

Study phase

PHASE2

Target enrollment

2 participants

Primary outcome timeframe

48 weeks

Results posted on

2021-11-24

Participant Flow

Participant milestones

Participant milestones
Measure
Treatment
(-)-epicatechin 50mg twice per day (100mg per day total dose) (-)-Epicatechin
Overall Study
STARTED
2
Overall Study
COMPLETED
2
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Treatment
n=2 Participants
(-)-epicatechin 50mg twice per day (100mg per day total dose) (-)-Epicatechin
Age, Continuous
54 years
n=2 Participants
Sex: Female, Male
Female
0 Participants
n=2 Participants
Sex: Female, Male
Male
2 Participants
n=2 Participants

PRIMARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

blood biomarker concentration

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

blood biomarker concentration

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

blood biomarker concentration

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

blood biomarker concentration

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

blood biomarker concentration

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

blood biomarker concentration

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

blood biomarker concentration

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

blood biomarker concentration

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

Ratio of plasma follistatin to plasma myostatin

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: baseline and at 2-minute intervals

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

blood lactate measured

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

Measurements recorded will include 25-meter split times and total distance traveled.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: 48 weeks

Population: Due to lack of funding, only 2 participants could be enrolled. The number of evaluable patients was insufficient to perform analysis of this outcome measure.

Collection of plasma samples for proteomics analysis.

Outcome measures

Outcome data not reported

Adverse Events

Treatment

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Craig McDonald, Professor and Chair

UC Davis Health

Phone: (916) 734-4293

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place