Trial Outcomes & Findings for Break It Up: A Study Evaluating Breaking Up Daily Sedentary Behavior in Youth (NCT NCT03223649)
NCT ID: NCT03223649
Last Updated: 2021-06-11
Results Overview
Insulin integrated area under the curve (iAUC) as a marker of glucose metabolism on OGTT during test day #6, collected at 0, 30, 60, 90, 120, 150, and 180 minutes after oral dextrose ingestion
Recruitment status
COMPLETED
Study phase
PHASE2
Target enrollment
129 participants
Primary outcome timeframe
test day 6
Results posted on
2021-06-11
Participant Flow
Participants were recruited via multiple methods: 1. Letters were mailed to local parents 2. Flyers were posted with permission. 3. Local community groups were asked to send the flyer to their listservs. 4. Schools, churches, pediatricians, and community centers were contacted. 5. Potential volunteers in ResearchMatch program were contacted.
Of the 129 participants who were evaluated with baseline screening, 20 were not studied further: * 12: Failed to meet inclusion criteria * 2: Impaired glucose tolerance * 1: Hepatic disease * 7: Failed picture vocabulary test * 2 Did not meet BMI criteria * 6: No longer interested * 1: Could not determine VO2 max or lactate threshold from exercise testing (insufficient effort) * 1: Withdrawn due to COVID pandemic restrictions
Participant milestones
| Measure |
Sedentary
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Overall Study
STARTED
|
52
|
57
|
|
Overall Study
COMPLETED
|
42
|
51
|
|
Overall Study
NOT COMPLETED
|
10
|
6
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Break It Up: A Study Evaluating Breaking Up Daily Sedentary Behavior in Youth
Baseline characteristics by cohort
| Measure |
Sedentary
n=42 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=51 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
Total
n=93 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
10.4 years
STANDARD_DEVIATION 1.3 • n=5 Participants
|
10.0 years
STANDARD_DEVIATION 1.2 • n=7 Participants
|
10.2 years
STANDARD_DEVIATION 1.3 • n=5 Participants
|
|
Sex: Female, Male
Female
|
18 Participants
n=5 Participants
|
27 Participants
n=7 Participants
|
45 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
24 Participants
n=5 Participants
|
24 Participants
n=7 Participants
|
48 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
6 Participants
n=5 Participants
|
8 Participants
n=7 Participants
|
14 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
36 Participants
n=5 Participants
|
43 Participants
n=7 Participants
|
79 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Asian
|
3 Participants
n=5 Participants
|
2 Participants
n=7 Participants
|
5 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Black or African American
|
9 Participants
n=5 Participants
|
5 Participants
n=7 Participants
|
14 Participants
n=5 Participants
|
|
Race (NIH/OMB)
White
|
27 Participants
n=5 Participants
|
38 Participants
n=7 Participants
|
65 Participants
n=5 Participants
|
|
Race (NIH/OMB)
More than one race
|
2 Participants
n=5 Participants
|
3 Participants
n=7 Participants
|
5 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
1 Participants
n=5 Participants
|
3 Participants
n=7 Participants
|
4 Participants
n=5 Participants
|
|
Region of Enrollment
United States
|
42 Participants
n=5 Participants
|
51 Participants
n=7 Participants
|
93 Participants
n=5 Participants
|
|
Fat Mass (kg)
|
16.2 kg
STANDARD_DEVIATION 12.4 • n=5 Participants
|
13.5 kg
STANDARD_DEVIATION 6.9 • n=7 Participants
|
14.7 kg
STANDARD_DEVIATION 9.8 • n=5 Participants
|
|
Lean Mass (kg)
|
28.9 kg
STANDARD_DEVIATION 7.9 • n=5 Participants
|
25.5 kg
STANDARD_DEVIATION 4.8 • n=7 Participants
|
27.0 kg
STANDARD_DEVIATION 6.6 • n=5 Participants
|
|
Height (cm)
|
146.0 cm
STANDARD_DEVIATION 9.8 • n=5 Participants
|
141.2 cm
STANDARD_DEVIATION 8.5 • n=7 Participants
|
143.4 cm
STANDARD_DEVIATION 9.4 • n=5 Participants
|
|
BMI (kg/m2)
|
21.2 kg/m2
STANDARD_DEVIATION 6.6 • n=5 Participants
|
19.9 kg/m2
STANDARD_DEVIATION 3.9 • n=7 Participants
|
20.5 kg/m2
STANDARD_DEVIATION 5.3 • n=5 Participants
|
|
BMI z-score
|
0.8 z-score
STANDARD_DEVIATION 1.2 • n=5 Participants
|
0.8 z-score
STANDARD_DEVIATION 0.9 • n=7 Participants
|
0.8 z-score
STANDARD_DEVIATION 1.0 • n=5 Participants
|
|
Fasting glucose (mg/dL)
|
87.6 mg/dL
STANDARD_DEVIATION 6.8 • n=5 Participants
|
87.9 mg/dL
STANDARD_DEVIATION 5.9 • n=7 Participants
|
87.8 mg/dL
STANDARD_DEVIATION 6.3 • n=5 Participants
|
|
Fasting insulin (mIU/ml)
|
11.1 mIU/mL
STANDARD_DEVIATION 9.8 • n=5 Participants
|
9.7 mIU/mL
STANDARD_DEVIATION 5.9 • n=7 Participants
|
10.4 mIU/mL
STANDARD_DEVIATION 7.4 • n=5 Participants
|
|
Peak VO2 (ml/kg/min)
|
38.3 ml/kg/min
STANDARD_DEVIATION 9.1 • n=5 Participants
|
38.5 ml/kg/min
STANDARD_DEVIATION 7.4 • n=7 Participants
|
38.4 ml/kg/min
STANDARD_DEVIATION 8.1 • n=5 Participants
|
|
IPAQ score
|
2.2 units on a scale (1-4)
STANDARD_DEVIATION 1.0 • n=5 Participants
|
2.2 units on a scale (1-4)
STANDARD_DEVIATION 1.1 • n=7 Participants
|
2.2 units on a scale (1-4)
STANDARD_DEVIATION 1.0 • n=5 Participants
|
PRIMARY outcome
Timeframe: test day 6Insulin integrated area under the curve (iAUC) as a marker of glucose metabolism on OGTT during test day #6, collected at 0, 30, 60, 90, 120, 150, and 180 minutes after oral dextrose ingestion
Outcome measures
| Measure |
Sedentary
n=42 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=51 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Insulin iAUC Obtained During the Oral Glucose Tolerance Test at the Final Experimental Visit.
|
13,698.60 mIU/dL∙min
Standard Deviation 9414.9
|
10,619.70 mIU/dL∙min
Standard Deviation 6,781.30
|
SECONDARY outcome
Timeframe: test day 6Integrated area under the curve (iAUC) for glucose values during the oral glucose tolerance test, collected at 0, 30, 60, 90, 120, 150, and 180 minutes after oral dextrose ingestion
Outcome measures
| Measure |
Sedentary
n=42 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=51 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Glucose iAUC Obtained During the Oral Glucose Tolerance Test on Day # 6 of Intervention.
|
22,247.90 mg/dL∙min
Standard Deviation 2,927.70
|
21,688.80 mg/dL∙min
Standard Deviation 2,473.70
|
SECONDARY outcome
Timeframe: test day 6Integrated area under the curve (iAUC) for C-Peptide values during the oral glucose tolerance test, collected at 0, 30, 60, 90, 120, 150, and 180 minutes after oral dextrose ingestion
Outcome measures
| Measure |
Sedentary
n=42 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=51 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
C-Peptide iAUC Obtained During the Oral Glucose Tolerance Test on Day # 6 of Intervention.
|
1,292.10 ng/dL∙min
Standard Deviation 449.8
|
1,160.10 ng/dL∙min
Standard Deviation 448.8
|
SECONDARY outcome
Timeframe: test day 6Integrated area under the curve (iAUC) for Free Fatty Acid values during the oral glucose tolerance test, collected at 0, 30, 60, 90, 120, 150, and 180 minutes after oral dextrose ingestion
Outcome measures
| Measure |
Sedentary
n=42 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=51 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Free Fatty Acid iAUC Obtained During the Oral Glucose Tolerance Test on Day # 6 of Intervention.
|
39.7 mmol/L∙min
Standard Deviation 9.8
|
38.5 mmol/L∙min
Standard Deviation 13.1
|
SECONDARY outcome
Timeframe: test days 1-6Population: Data were unavailable from two participants randomized to the Sedentary condition and from one participant randomized to the Walking Bouts condition.
Mean 3-dimensional activity during the 3 hours of intervention from all days (step counts per minute)
Outcome measures
| Measure |
Sedentary
n=40 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=50 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Daily Physical Activity (Step Counts/Min) During Intervention.
|
5.4 step count per minute
Standard Deviation 1.9
|
11.2 step count per minute
Standard Deviation 3.0
|
SECONDARY outcome
Timeframe: test days 1-6Population: Data were unavailable from two participants randomized to the Sedentary condition and from one participant randomized to the Walking Bouts condition.
Mean total daily 3-dimensional activity counts during the 21 hours without intervention on days 1-6 (activity counts/21 hours) from triaxial write accelerometers worn at home. Note: these are not "step counts" but total 3D activity counts because motion of the wrist at times other than walking are also recorded. There is no simple way to convert these counts to step counts.
Outcome measures
| Measure |
Sedentary
n=40 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=50 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Daily Physical Activity (3-dimensional Activity Counts/Day) Outside of the Intervention.
|
2.1 activity counts per 21 hours x 10^6
Standard Deviation 0.6
|
2.2 activity counts per 21 hours x 10^6
Standard Deviation 0.5
|
SECONDARY outcome
Timeframe: test day 6Population: Data were unavailable from two participants randomized to the Sedentary condition and from two participants randomized to the Walking Bouts condition.
Total energy intake (kcal) during buffet meal immediately after the end of intervention
Outcome measures
| Measure |
Sedentary
n=40 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=49 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Energy Intake at the Final Test Meal.
|
1,312.4 kcal
Standard Deviation 478.4
|
1,207.4 kcal
Standard Deviation 443.8
|
SECONDARY outcome
Timeframe: test day 6Population: Data were unavailable from two participants randomized to the Sedentary condition and from two participants randomized to the Walking Bouts condition.
Percentage Energy intake from Fat during buffet meal immediately after the end of intervention
Outcome measures
| Measure |
Sedentary
n=40 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=49 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Percentage Fat Intake at the Final Test Meal.
|
35.8 percentage of total energy intake (%)
Standard Deviation 7.0
|
36.2 percentage of total energy intake (%)
Standard Deviation 6.0
|
SECONDARY outcome
Timeframe: test day 6Population: Data were unavailable from two participants randomized to the Sedentary condition and from two participants randomized to the Walking Bouts condition.
Percentage Energy intake from Carbohydrate during buffet meal immediately after the end of intervention
Outcome measures
| Measure |
Sedentary
n=40 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=49 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Percentage Carbohydrate Intake at the Final Test Meal.
|
52.0 percentage of total energy intake (%)
Standard Deviation 9.0
|
51.8 percentage of total energy intake (%)
Standard Deviation 8.4
|
SECONDARY outcome
Timeframe: test day 6Population: Data were unavailable from two participants randomized to the Sedentary condition and from two participants randomized to the Walking Bouts condition.
Percentage Energy intake from Protein during buffet meal immediately after the end of intervention
Outcome measures
| Measure |
Sedentary
n=40 Participants
(Control intervention) Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
Sedentary: (Control 'intervention') Six daily 3 hour sessions with no physical activity (i.e. subject remains sedentary in seated or recumbent position) throughout the 3 hour duration.
|
Walking Bouts
n=49 Participants
Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory thresholdas determined during a V02max test.
Walking Bouts: Six daily 3 hour sessions with prompted 3-minute moderate-intensity walking bouts performed on a treadmill every 30 minutes throughout the 3 hour duration. There will be a total of 6 walking bouts (18 minutes total) each day. Moderate-intensity walking speed and grade will be selected to achieve 80% of the heart rate achieved at the ventilatory threshold as determined during a V02max test.
|
|---|---|---|
|
Percentage Protein Intake at the Final Test Meal.
|
12.2 percentage of total energy intake (%)
Standard Error 3.6
|
12.0 percentage of total energy intake (%)
Standard Error 3.2
|
Adverse Events
Sedentary
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Walking Bouts
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place